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Materias / palabras clave: Virology; Virología

ABSTRACT Background and Aims Human metapneumovirus (hMPV) is a leading cause of acute respiratory tract infections, particularly in children, older adults, and individuals with immunocompromising conditions. Despite incr...

Abstract Rift Valley fever (RVF) is a mosquito-borne zoonosis of major concern for human and animal health, yet no licensed human vaccine exists. Here, we engineered a self-assembling nanoparticle vaccine candidate by ge...

Inborn errors of immunity (IEI) can manifest with neurological disorders, indicating genetic overlap between immune and nervous system diseases. However, neurological disorder genes are rarely screened systematically for...

Abstract Therapeutic human papillomavirus (HPV) DNA vaccine is an attractive option to control existed HPV infection and related lesions. The two early viral oncoproteins, E6 and E7, are continuously expressed in most HP...

Abstract Bacteriophages constitute a major component of the human gut virome, playing very important roles in shaping of the structure and function of the gut microbiota. Moreover, bacteriophages interact with the human ...

Abstract Canine coronavirus type II (CCoV-II), an alphacoronavirus, is responsible for mild enteritis, especially in puppies, but due to its plasticity, it can also cause serious diseases in humans. Formyl peptide recept...

Abstract Background Herpes simplex virus type 1 (HSV-1) is a common human pathogen of herpes simplex keratitis (HSK), one of the leading causes of infectious blindness worldwide. Antiviral therapies remain limited by the...

Abstract Influenza A virus (IAV) infections play a substantial role in human disease, hospitalization, and economic loss. In an effort to better understand the intracellular effects that IAV replication has on individual...

Abstract Background Temperate phages play a central role in the evolution and pathogenicity of Staphylococcus aureus. Sa3int phages provide highly human-specific virulence factors that promote immune evasion and survival...

A recent report that 93 per cent of invasive cervical cancers worldwide contain human papillomavirus (HPV) may be an underestimate, due to sample inadequacy or integration events affecting the HPV L1 gene, which is the t...

Abstract Emerging infectious diseases, such as severe acute respiratory syndrome (SARS) and Zika virus disease, present a major threat to public health 1–3 . Despite intense research efforts, how, when and where new di...

Materias / palabras clave: Infectivity; DNA; Biology; Molecular biology; Calcium; Virus; Cell culture; Incubation; Virology; Biochemistry; Chemistry; Genetics

Abstract Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural reservoir host, bats 1–4 . Previous ...

BACKGROUND: The initial cases of novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, Hubei Province, China, in December 2019 and January 2020. We analyzed data on the first 425 confirmed cases in W...

Materias / palabras clave: human viruses, plant viruses, antiviral agents, vaccines, animal viruses, infection control; Medicine: Internal medicine: Infectious and parasitic diseases

Materias / palabras clave: human virology, infectious disease, epidemiology, virus infection, diagnosis; Medicine: Internal medicine: Infectious and parasitic diseases