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IntroductionIn co-endemic regions, hosts are concurrently infected by related apicomplexan hemoparasites, Plasmodium and the zoonotic pathogen Babesia. This study investigates how Plasmodium berghei XAT-Babesia rodhaini ...

Plant nucleotide-binding leucine-rich repeat receptors (NLRs) function in both shoots and roots as key components of plant immunity, yet their biological roles in roots remain poorly understood. Here, we established a co...

OBJECTIVE: End-stage renal disease (ESRD) patients are more prone to serious influenza virus infection than healthy subjects. Selenium (Se) play an important role in cellular and humoral immunity and serum Se levels were...

Abstract Acquired immunity in plants, including systemic acquired resistance (SAR) and induced systemic resistance (ISR), plays a central role in protecting crops against a wide spectrum of pathogens and pests, ranging f...

Inborn errors of immunity are a group of genetic disorders caused by mutations that affect the development and/or function of several compartments of the immune system, predisposing patients to infections, autoimmunity, ...

Abstract This study aimed to investigate the effectiveness of carotenoid supplementation on the performance, egg quality, and immunity of laying hens using a meta-analysis approach. The database was searched using Google...

The interplay between thyroid hormone action and the immune system has been established in physiological and pathological settings. However, their connection is complex and still not completely understood. The thyroid ho...

Materias / palabras clave: cancer immunity; DC vaccines; DC-based cell therapy; dendritic cells; immunotherapy

Materias / palabras clave: coagulation; complement; endothelium; hematological disorders; innate immunity; thromboinflammation

Tomato (Solanum lycopersicum), along with many other economically valuable species, belongs to the Solanaceae family. Understanding how plants in this family defend themselves against pathogens offers the opportunity of ...

Background and Aim: Mycotoxin contamination in poultry feed, particularly aflatoxin B1 (AFB1) and ochratoxin-A (OTA), induces immunosuppression and compromises vaccine efficacy, leading to substantial economic losses in ...

IntroductionIndividuals with inborn errors of immunity (IEI) are increasingly reaching reproductive age, yet guidance on fertility preservation, genetic counseling, medication adjustments in pregnancy and breastfeeding, ...

The composition of the upper respiratory tract (URT) microbiota is shaped by both anatomical niches and host immune defenses. Older adults (>65 years) are at greatest risk of acquiring severe URT infections. However, ver...

BackgroundAluminum (Al) is a lightweight metal that is widely present in the environment and the human body. It has been documented to cause various adverse health effects including the suppression of humoral immunity.Ob...

One foundational goal of global health and a shared inspiration for all humankind is to reduce premature mortality from preventable and treatable conditions. This imperative becomes markedly more urgent for the uniquely ...

Opioids remain central to managing moderate to severe pain, yet they also produce significant and often under-recognized effects on the immune system. In this narrative review, we synthesize evidence from 1994 to 2025 ac...

BackgroundNewborn screening (NBS) with kappa-deleting recombination excision circles (KRECs) is primarily used to detect B cell lymphopenia and agammaglobulinemia as markers of inborn errors of immunity (IEIs). However, ...

Abstract Ebola viral disease, or simply Ebola is a fatal and highly contagious disease caused by the Ebolavirus. Macrophages and dendritic immune cells are the predominant target cells of Ebolavirus. In this present stud...

RationaleInborn errors of immunity (IEIs) predispose individuals to recurrent respiratory infections and immune dysregulation, which together can drive inflammatory lung complications, including interstitial lung disease...

IntroductionRecent research has highlighted the role of the gut microbiome in shaping the development and function of the mammalian immune system. Interactions between these complex networks of microbes and host cells se...

The pathogenesis of Plasmodium falciparum malaria is linked to the variant surface antigen PfEMP1, which mediates tethering of infected erythrocytes to the host endothelium and is encoded by approximately 60 var genes pe...

Abstract Vaccines represent the most cost-effective and efficacious approach for preventing gastrointestinal infections, and adjuvants play a pivotal role in enhancing and modulating immune responses. In this article, ...

The rapid annual increase in conditions classified as inborn errors of immunity (IEI), along with associated genetic variants, creates diagnostic challenges. The comprehensive nature of exome sequencing (ES) and genome s...

Chronic norovirus infection (CNI) causes significant morbidity and mortality in immunocompromised patients, including those with inborn errors of immunity (IEI). Gastrointestinal samples from patients with CNI demonstrat...