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Radiotherapy and immunotherapy for advanced cancers: A meta-analysis of dose, sequencing, and survival patterns

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Radiotherapy and immunotherapy for advanced cancers: A meta-analysis of dose, sequencing, and survival patterns

Xun-Jie Cao et al · Elsevier · 2026 · ISSN 1936-5233

Background: Combining radiotherapy (RT) with immune checkpoint inhibitors (ICIs) offers potential synergy through RT-induced immunogenic cell death and enhanced systemic immunity. However, optimal RT dose, fractionation,...

LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng

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The natural flavonoid dihydromyricetin targets senescent cells via PRDX2 and alleviates age-related diseases

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The natural flavonoid dihydromyricetin targets senescent cells via PRDX2 and alleviates age-related diseases

Qixia Xu et al · Nature Portfolio · 2026 · ISSN 2041-1723

Abstract Aging is a primary risk factor for chronic diseases, with cellular senescence as an effective target to delay, prevent or alleviate age-related disorders. Here we report in vitro screening outputs from a natural...

LCC TENDOlNjaWVuY2U~Idioma eng

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Transcribing historical Canadian weather data

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Transcribing historical Canadian weather data

Victoria Slonosky et al · Nature Portfolio · 2026 · ISSN 2052-4463

Abstract Historical weather journals from across Canada, spanning 1768–1884, have been transcribed from handwritten records into machine readable formats. The NORTHERN (Nineteenth-century Overseas Records Transcribed f...

LCC TENDOlNjaWVuY2U~Idioma eng

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Use of Sirolimus and Immunoglobulin Replacement Therapy (IRT) in Patients with Activated Phosphoinositide 3-Kinase Delta Syndrome (APDS): A Systematic Literature Review (SLR)

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Use of Sirolimus and Immunoglobulin Replacement Therapy (IRT) in Patients with Activated Phosphoinositide 3-Kinase Delta Syndrome (APDS): A Systematic Literature Review (SLR)

Nicholas L. Hartog et al · Rockefeller University Press · 2026 · ISSN 3065-8993

IntroductionActivated Phosphoinositide 3-Kinase Delta Syndrome (APDS), a rare inborn error of immunity, is associated with immunodeficiency and immune dysregulation. Clinical management includes symptomatic treatment wit...

LCC LCC:Immunologic diseases. AllergyIdioma eng

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Glucocorticoids suppress early lung inflammation and impair control of SARS-CoV-2 in non-human primates.

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Glucocorticoids suppress early lung inflammation and impair control of SARS-CoV-2 in non-human primates.

Christine E Nelson et al · Public Library of Science (PLoS) · 2026 · ISSN 1932-6203

In severe cases of COVID-19, glucocorticoid treatment improves clinical outcomes. However, in non-hospitalized patients, glucocorticoids have limited benefit and may impair viral clearance. Here, we used the rhesus macaq...

LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng

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