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Carotid artery stenting (CAS) has emerged as an effective alternative to carotid endarterectomy for treating carotid artery stenosis, particularly in high-risk surgical patients. However, in-stent restenosis (ISR) remain...

ObjectiveThis study aimed to evaluate the predictive value of combining visceral fat area (VFA) with blood lipid levels for perioperative risk and long-term prognosis in patients undergoing radical resection for colorect...

Abstract Ornithine lipids (OLs) are phosphorus-free membrane lipids present in many bacteria, but absent from eukaryotes and archaea. Three pathways for OL synthesis have been reported to date. Conditions that induce OL ...

Abstract Senescent cells (SnCs) are increasingly recognized as key contributors to osteoarthritis, with conventional strategies centered on their elimination. However, senolytic approaches face mounting limitations, driv...

High-altitude environments impose substantial metabolic constraints on human physiology, with oxygen limitation driving profound alterations in lipid regulation. This narrative review synthesizes current evidence on the ...

Rosacea is a chronic inflammatory skin disorder primarily characterized by persistent facial erythema, episodic flushing, papules and pustules, as well as phymatous changes. Despite extensive research, the pathogenesis o...

Abstract Hesperidin (HSP) is a bioactive flavonoid, and its activity is limited due to poor water solubility. We designed this research to develop and evaluate hesperidin nanoparticles (HSPNPs) to enhance drug release an...

Abstract Understanding the kinetics of nanoparticle vaccine drainage to the lymph nodes and their residence time in these tissues is critical in vaccine development. Evaluating these parameters using conventional techniq...

Abstract Background Evidence regarding health effects of ultra-processed food (UPF) in children is scarce and contradictory. Therefore, the aim was to assess the associations between UPF intake and anthropometric measure...

Abstract Despite the extensive use of synthetic and semi-synthetic lipids in nanostructured lipid carrier (NLC) systems, the utilization of Shorea spp. (Illipe butter or tengkawang fat), an indigenous natural solid lipid...

Surface adhesion is critical to the survival of pathogenic bacteria both in natural niches and during infections, often via forming matrix-embedded communities called biofilms. Vibrio cholerae, the causal agent of pandem...

Abstract A recent dietary trend involves replacing cow’s milk with plant-based drink alternatives. This shift is motivated by the perception that plant-based options are healthier and more environmentally sustainable. ...

Chlorella micro algae strains offer sustainable biomass feedstocks in biofuel production because of their resilience, diversity, high adaptability to environmental stresses, flexible cultivation alternatives and high bio...

Abstract Fatty acid ethanolamides (FAEs) are bioactive lipids with amphiphilic properties and potential as prodrugs. In this study, a homologous series of FAEs (C8:0–C18:0) was evaluated for solubility, hydrophobicity,...

Abstract Diminished ovarian reserve (DOR) lacks strong plasma biomarkers, and recent studies have implicated lipid remodeling in its pathophysiology. In our previous study, we noted elevated circulating levels of semapho...

Abstract The human lipidome comprises numerous complex lipids, dysregulation of which can contribute to the pathogenesis of a wide range of diseases. Despite the high heritability of parts of the lipidome, the genetic ar...

Abstract Background This study examined the associations of reallocating time among 24-hour movement behaviors (24HMB) on cardiometabolic health outcomes (anthropometric indicators, blood pressure, glucose, lipids) in ad...

Abstract Background Polycystic ovary syndrome (PCOS) is characterised by insulin resistance and hyperandrogenism; whether novel antidiabetic drugs differentially improve these metabolic and reproductive disturbances rema...

The extensive reliance on fossil resources for fuels and platform chemicals has raised critical concerns over resource depletion and increasing greenhouse gas emissions. To address these challenges, microalgae offer a pr...

Gastrodia elata Blume, a traditional medicinal plant, the dynamic metabolic changes and the mechanisms underlying the accumulation of medicinal components remain poorly understood during its key developmental stages (tub...