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Abstract Sickle Cell Disease (SCD) remains a significant global health burden, disproportionately affecting low- and middle-income countries (LMICs), particularly in sub-Saharan Africa. Recent advancements in gene-based ...

Abstract Human papillomavirus (HPV) vaccination is a safe and cost-effective strategy for preventing cervical cancer, yet uptake remains low worldwide, particularly in low- and middle-income countries (LMICs). Numerous i...

Aims: Acute hand and wrist infections can be devastating, with a substantial burden in low- and middle-income countries (LMICs) compared with high-income countries. Access to treatment, particularly surgery, can be limit...

Abstract Background Strengthening urban primary healthcare (PHC) systems in low- and middle-income countries (LMICs) is essential to effectively serve the growing urban poor. Such reforms should incorporate patient opini...

Abstract Global strategies to improve newborn survival have expanded from basic Essential Newborn Care practices to more comprehensive approaches that address the specific needs of small and sick newborns. Despite advanc...

Abstract BackgroundThe Sustainable Development Goals (SDGs) aim to eradicate poverty and inequality while ensuring that all individuals enjoy good health. Among these, target 3.1 seeks to reduce the global ma...

Abstract Background Lung cancer surgery in low- and middle-income countries (LMICs) is frequently challenged by late-stage presentation, high comorbidity burden, and limited healthcare resources. Although video-assisted ...

BackgroundImmune checkpoint inhibitors (ICIs) have markedly improved outcomes in metastatic microsatellite instability-high (MSI-H) or deficient mismatch repair (dMMR) gastrointestinal (GI) malignancies. However, in frag...

Abstract Introduction There have been increasing concerns about the possible high prevalence of chronic kidney disease (CKD) among returnee Nepalese migrant workers from the Gulf countries and Malaysia. This population-b...

ABSTRACT Background and Aim Undernutrition is gradually declining worldwide except in sub‐Saharan Africa and parts of South Asia. Prevalence is almost stagnant in low‐and middle‐income countries (LIMCs), contributi...

ABSTRACT Background Managing biomedical waste (BMW) effectively is a pressing public health challenge, particularly in low‐resource settings in accordance with the World Bank classification of low‐ and middle‐incom...

This study investigates the health impacts of transitioning from Gavi, the Vaccine Alliance, on vaccination coverage, infant and under-5 mortality, and disability-adjusted life years (DALYs) in low and middle-income coun...

ABSTRACT Background and Aims Preeclampsia remains a leading cause of maternal and perinatal morbidity and mortality globally, with high incidence and case fatality rates in low‐ and middle‐income countries (LMICs). E...

Abstract Although information on minor blood group antigen frequencies is limited in many low- and middle-income countries, extended red blood cell (RBC) phenotyping is crucial for reducing alloimmunization in patients u...

Introduction Tuberculosis (TB) remains a significant health burden in 25 low- and middle-income countries. Despite TB being more cost-effective to prevent and treat its funding is disproportionately lower than that of HI...

Background: As populations age and hypertension prevalence rises, the burden of hypertension-attributable chronic kidney disease (CKD) keeps aggregating and varies across regions. A systematic assessment of how disease b...

Abstract Background Epidermolysis bullosa (EB) is a rare genetic disorder that causes extreme skin fragility, chronic pain, and functional impairment, with major psychosocial and economic consequences. Health-related qua...

This article aims to create country profiles for European Union Member States, based on indicators that capture digital access and usage, business digitalisation and e-commerce, as well as human capital and innovation ca...

Against the global backdrop of accelerating climate change and the urgent need for energy transition, understanding the role of protected areas in shaping renewable energy consumption has become increasingly important. U...

Abstract Background Silicosis is an irreversible scarring lung disease caused by occupational respirable crystalline silica (RCS) dust exposure. Mineral (noncoal) miners who extract metal, nonmetal, stone, and sand/grave...

Purpose — This study investigates the impact of economic complexity on income levels across countries at different stages of economic development, with particular emphasis on how these effects vary across the income di...

Abstract Background The use of antipsychotic drugs has increased in recent years, extending beyond traditional indications like schizophrenia and bipolar disorder while the use of lithium has remained stable or declined....

Abstract Background There is little evidence on the association between cooking with polluting fuels, particularly charcoal, and heart disease from low- and middle-income countries, which have the highest burdens of poll...

IntroductionA research gap exists regarding the association between non-optimal ambient temperature (NOAT) and early childhood development (ECD) in low- and middle-income countries (LMICs). This study investigates the as...