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A 64-year-old female presented to the emergency department with complaints of fatigue, diarrhea, dizziness, and fever. Initial evaluation revealed hyperkalemia and primary adrenal insufficiency. Computed tomography of th...

In glomerular diseases, the occurence of lymphoma is mostly observed in the form of both minimal change disease and Hodgkin’s lymphoma. The coocurrence of Membranous nephropathy and membranoproliferative glomerulonephr...

Hodgkin’s lymphoma is a malign disease of lmyphatic system. It’s known that, chronic renal failure may occur as a result of glomerular pathology which develops due to malign diseases. But, association of Hodgkin’s ...

ABSTRACT This study aimed to characterize the epidemiological and immunohistochemical aspects of canine indolent T-zone lymphoma and to evaluate the Ki67 cut-off point for differentiating T-zone lymphomas from high-grade...

Abstract Background Current tests for diagnosis and differentiation of lymphoplasmacytic enteritis (LPE) and small cell lymphoma (SCL) in cats are expensive, invasive, and lack specificity. The identification of less inv...

Abstract Objective To evaluate the cost-effectiveness of zanubrutinib compared to ibrutinib in the first-line treatment of chronic lymphocytic leukemia (CLL) / small lymphocytic lymphoma (SLL) from the perspective of the...

ABSTRACT Lymphoma is the most common lymphoproliferative disorder in cats. However, cutaneous lymphomas are uncommon in this species and can be classified as epitheliotropic or non-epitheliotropic. Epitheliotropic lympho...

Abstract Background Patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) who failed bispecific antibody (BsAb) therapy face an extremely poor prognosis, necessitating exploration of effective salva...

Background: Mantle cell lymphoma (MCL) exhibits distinct biological characteristics and marked molecular heterogeneity, with TP53 mutations associated with particularly poor clinical outcomes. Eprenetapopt (APR-246), a f...

Abstract Background Hypercalcemia of malignancy (HM) secondary to lymphoma in dogs has the potential to cause renal injury. Hypothesis/Objectives Characterize outcomes related to acute kidney injury (AKI) secondary to HM...

Background and purpose: Mediastinal lymphoma patients are typically young and are at risk of long-term radiation-induced adverse events, making organ of interest (OOI) sparing a key objective of radiotherapy. This study ...

Hodgkin’s Lymphoma (HL) is the most common malignancy among Adolescents and Young Adults (AYAs). Although survival rates are excellent, two thirds of survivors experience physical and psychosocial late effects that can...

Background Doxorubicin is a common antineoplastic agent with dose‐dependent cardiotoxic adverse effects, and pre‐existing myocardial dysfunction is a contraindication to its use. Objectives To systematically define t...

Hyaluronan (HA) modulates multidrug resistance (MDR) as well as cell migration. Tiam1 is involved in cytoskeleton reorganization during tumor invasion. In this report we show the relationship among HA, Tiam1, migration a...

Objectives Lactylation and liquid–liquid phase separation related genes have been reported to be associated with tumor prognosis and immunity, but their specific influence on the prognosis and immune characteristics of...

Abstract Background Diffuse large B-cell lymphoma (DLBCL) is an aggressive subtype of non-Hodgkin lymphoma. Fatty acid synthase (FASN) is a key lipogenic enzyme implicated in tumor progression, but its regulation in DLBC...

BackgroundPatients with lymphoma frequently experience significant psychosocial burden, including anxiety, depression, and impaired quality of life, which may persist throughout the disease trajectory. Coping strategies ...

CD5 positive diffuse large B cell lymphoma is a very rare subtype of diffuse large B cell lymphoma with an aggressive lymphoid neoplasm. Extranodal involvement of lymphoma usually appears secondarily in the setting of di...

Kaposi’s sarcoma-associated herpesvirus (KSHV) is a DNA virus linked to multiple malignancies associated with compromised immunity, such as Kaposi’s sarcoma (KS) and primary effusion lymphoma (PEL). These malignancie...

Ziyuan Shen,1 Xing Xing,2 Kang Rong,3 Ziyang Geng,4 Ning Yang,5 Linyan Xu,3,6 Hongfeng Ge,7 Wei Sang3,6,8 1Clinical Research Institute, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, People’s Re...

BackgroundTransmembrane Emp24 Domain Containing 2 (TMED2) is involved in various cancers, but its role in diffuse large B-cell lymphoma (DLBCL) remains unclear. This study investigated TMED2’s expression, biological fu...

BackgroundDiffuse large B-cell lymphoma (DLBCL), the most common non-Hodgkin lymphoma, exhibits genetic heterogeneity and variable treatment responses. Discovering new therapeutic targets is critical to improve outcomes....

Abstract Background Primary central nervous system lymphoma (PCNSL) can be differentiated from glioblastoma multiforme (GBM) using positron emission tomography (PET) with [18F]fluoro-2-deoxy-D-glucose (FDG). However, dif...

Adoptive therapy with CD19 chimeric antigen receptor (CAR) T cells is effective against B-cell malignancies; however, T-cell activation rapidly declines, increasing the risk of early leukemia relapses. To augment CD19 CA...