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The extensive reliance on fossil resources for fuels and platform chemicals has raised critical concerns over resource depletion and increasing greenhouse gas emissions. To address these challenges, microalgae offer a pr...

ObjectiveCoals are highly sensitive to variations in temperature and pressure conditions. The structural evolution of coal macromolecules, driven by tectono-thermal processes, is the key to understanding coal rank transi...

Scleroderma is a systemic autoimmune disease of unknown origin characterized by excessive deposition of collagen and other connective tissue macromolecules in multiple organs. It can cause thrombotic microangiopathy. Scl...

Plasmapheresis is a method of cleaning the high molecular weight solutes such as immune complexes, protein-bound toxins, autoantibodies, cryoglobulins, myeloma light chains, and endotoxins from the extracorporeal blood p...

Abstract Autophagy plays an important role in maintaining cell homeostasis through degradation of denatured proteins and other biological macromolecules. In recent years, many researchers focus on mechanism of autophagy ...

The capillary wall of the glomerulus, which is composed of glomerular endothelial cells (GECs), the glomerular basement membrane (GBM), and podocytes, is responsible for the ultrafi ltration of plasma in the kidney. The ...

Biologic therapeutics have transformed the treatment of chronic and life-threatening diseases, yet their clinical use depends almost entirely on parenteral administration. Oral delivery is the preferred route for patient...

OBJECTIVES: Oxidative stress (OS) is the most important common pathway in the pathogenesis of endothelial and vascular damage related with the cardiovascular risk factors. Reactive oxygen species damage the macromolecu...

Affinity partitioning combines the partitioning behavior of biological macromolecules in aqueous two phase systems with the principle of biorecognition. Among the numerous substances that have been evaluated as ligands,...

Photodynamic priming (PDP), a collateral effect of photodynamic therapy, can transiently alter the tumor microenvironment (TME) beyond the cytotoxic zone. Studies have demonstrated that PDP increases tumor permeability a...

Proteins are fundamental biological macromolecules responsible for a wide range of cellular functions. Traditionally, a central paradigm linked the amino acid sequence to a unique, ordered three-dimensional structure tha...

Plasmapheresis is an extracorporeal procedure, which is often employed to rapidly lower circulating titers of autoantibodies, immune complexes or toxins. There are two types of plasmapheresis namely, regular plasmapheres...

Los copolímeros en bloques están formados por macromoléculas constituidas por bloques poliméricos dispuestos en una secuencia lineal. Entre los copolímeros en bloques con aplicaciones farmacéuticas se destacan los ...

An account is given of the development of the SHELX system of computer programs from SHELX-76 to the present day. In addition to identifying useful innovations that have come into general use through their implementation...

Coot is a molecular-graphics application for model building and validation of biological macromolecules. The program displays electron-density maps and atomic models and allows model manipulations such as idealization, r...

We report a method to form multifunctional polymer coatings through simple dip-coating of objects in an aqueous solution of dopamine. Inspired by the composition of adhesive proteins in mussels, we used dopamine self-pol...

The Protein Data Bank (PDB; http://www.rcsb.org/pdb/ ) is the single worldwide archive of structural data of biological macromolecules. This paper describes the goals of the PDB, the systems in place for data deposition ...

Materias / palabras clave: eukaryotic cell biology, prokaryotic cell biology, molecular biology, biological macromolecules; Science: Biology (General): Cytology

Materias / palabras clave: monomers, polymers, macromolecules, macroinitiators; Technology: Chemical technology: Polymers and polymer manufacture

Materias / palabras clave: macromolecules, supramolecular chemistry, assembly, bio-inspired surfaces, soft-matter, hybrid materials; Science: Science (General)