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The diversity of Sarcocystis spp. infecting Alaskan marine mammals is largely unknown, which is relevant in a region of the world where hunting and consumption of marine mammals is essential to Alaskan native food securi...

Abstract Fear and pain are two frequently co-occurring states that mammals need to orchestrate to ensure survival. Nevertheless, how the brain dynamically prioritizes between them remains poorly understood. Here, we demo...

Abstract The mechanisms by which core clock components are spatially organized to ensure robust oscillations in mammals remain unclear. Here, we identify the positive limb factor BMAL1 as a phase-separating protein that ...

Abstract Passive acoustic monitoring (PAM) of marine mammals is essential for biodiversity monitoring and communication studies. Tracking animals in situ further enables behavioral investigation. Monitoring from boats, t...

Background The field of extracellular vesicles (EVs) has advanced considerably in recent years with new findings stemming from technical improvements in their isolation and characterization, expanding their potential as ...

Abstract Background Follicular development is a prerequisite for vertebrate reproduction, and it is precisely regulated by complex genomic conformations and regulatory elements. However, the dynamic changes in the intera...

Abstract Background Progressive retinal atrophy (PRA) was diagnosed in four related male English Cocker Spaniels (ECS) between the ages of 3 and 4 years. All affected dogs were born to clinically unaffected parents that ...

Abstract Effective management decisions rely on accurate insights into species’ population structure, with high-quality genetic material being essential. Stranded cetaceans are an important source of samples, but meeti...

Pigment anomalies such as leucism and albinism are rare in wild mammals, often linked to genetic or developmental factors and sometimes carry ecological consequences. Here, we report the first record of leucism in the Ro...

Abstract The genomic locus that encodes the Leucine-rich repeat kinase 2 (LRRK2) gene is highly pleiotropic and associated with Parkinson’s disease (PD). Coding variants associated with risk of PD act as gain of functi...

Abstract The use of animal-borne devices to measure acceleration has yielded insights into animal locomotion, behaviour and energy expenditure. We present the first systematic review of accelerometry on animals, spanning...

Abstract Antlers are the fastest-growing osseous tissue in mammals, undergoing periodic regeneration associated with the mating season. Their high strength and resistance to fracture have made them a valuable material fo...

Abstract Background Animals rely on symbiotic bacteria living within/on their tissues for multiple functions, while simultaneously needing to protect themselves via immune functions or other defenses from potentially pat...

Abstract Despite intense investigation through centuries, there is still no scientific consensus on how to describe myocardial microarchitecture. This is mainly because the myocardium must be visualised in three dimensio...

Abstract Selenoproteins incorporate the rare selenium-containing amino acid selenocysteine (Sec) and play crucial roles for redox homeostasis, stress response, and hormone regulation. Sec is inserted by co-translational ...

Abstract The first truly terrestrial apex predators were carnivorous synapsids, which emerged in the Permian over 260 million years ago and evolved against a backdrop of harsh ecological change. In many ways, these preda...

Abstract Vertebrate chemoreceptor genes play a central role in detecting environmental chemical compounds through the olfactory organs and taste buds, enabling the perception of odors and tastants that are critical for s...