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The study evaluates the use of medications by pregnant women attended at health centers in the city of Campina Grande-PB, Brazil. The sample consisted of 250 patients. The number of prescribed medications ranged from 1 t...

Abstract Background Previous studies have indicated potential associations between some drugs and cancer risk, but the causal relationship with gastric cancer remains unclear. This study aimed to explore the causality be...

Abstract Background Many individuals with bipolar disorder have decreased levels of cognitive functioning even when in a euthymic mood state. Persons with bipolar disorder are usually treated with psychotropic agents, bu...

Abstract Background Antiseizure medications (ASMs) are essential for seizure control, but they are also associated with a range of adverse events that may affect treatment outcomes. Objective This study aimed to evaluate...

Antimalarial drugs used in medicine for over 300 years, nowadays, due to their anti-inflammatory, immunomodulatory and antiproliferative photoprotective properties, are used in the therapy of many dermatologic and rheuma...

BackgroundThis study examines the effect of initiating medications with anticholinergic activity on the cognitive functions of older persons.MethodsParticipants were 896 older community-dwelling, Catholic clergy without ...

Abstract Introduction Glecaprevir/pibrentasvir (G/P) is globally approved for the treatment of chronic hepatitis C virus (HCV) infection and for acute HCV infection in the USA. The efficacy and safety of G/P has been cl...

Background: Potentially inappropriate medications (PIMs) disproportionally affect the quality of life of patients aged 65 years or older and are associated with increased direct healthcare costs. However, evidence on the...

Abstract Background Diabetes is associated with a high incidence of diabetic foot and peripheral artery disease and with markedly increased lifetime amputation risk. Here we investigated predictors of reamputation risk a...

Abstract Importance The mortality benefit of lipid-lowering therapies (LLTs) in true primary prevention of cardiovascular disease (CVD) remains uncertain, in part because prior studies frequently included individuals wit...

This study is the first attempt in UAE to prove the trustworthiness of the in vitro evaluation to assess the reliability of the generic medications comparing to the brand name. Five generic medicines, two Local (codes: L...

Abstract Objective: Despite the literature on dydrogesterone, studies on dydrogesterone utilization patterns are largely lacking in Indian patients. Methods: This was a multi-center, retrospective, observational, cross...

Abstract Background The global rise in adolescent obesity is driving an aggressive phenotype of type 2 diabetes (T2D), which is marked by rapid progression and premature mortality. Therefore, evidence-based, internationa...

Abstract Background/Objective Asthma medication adherence, measured by the asthma medication ratio (AMR), has been shown to be a reliable predictor of exacerbations among children with asthma. We developed a Markov model...

IntroductionIndividuals with inborn errors of immunity (IEI) are increasingly reaching reproductive age, yet guidance on fertility preservation, genetic counseling, medication adjustments in pregnancy and breastfeeding, ...

Background Antiseizure medications (ASMs) are the standard treatment for epilepsy. Yet because ASMs can have adverse effects and seizure risk decreases with longer seizure-free periods, guidelines have suggested consider...

Abstract Background Diabetes is a major global public health burden. Effective diabetes management is highly dependent on the availability of affordable and quality-assured essential medicines (EMs) which is a challenge ...

BackgroundPhakic intraocular lenses (pIOLs), used to correct high refractive errors, have since been associated with long-term complications including glaucoma and cataract formation. Elevated intraocular pressure (IOP) ...

Background: Carbon footprint quantification currently stands as the most accepted model for assessing the ecological impact of human activities.Selecting the most environmentally friendly treatment for pathologies arisin...

ABSTRACT Background According to global projections, by the year 2050, ischemic heart disease will remain the leading cause of cardiovascular deaths with hypertension as a leading modifiable risk factor for mortality. Im...

Abstract Background Managing the simultaneous treatment of HIV/AIDS and tuberculosis (TB) increases the risk of adverse reactions, drug interactions, and challenges to treatment adherence. To address these complexities, ...

ABSTRACT Background and Aims Limited evidence suggests autoimmune thyroiditis (AT) could represent a risk factor for cervical artery dissection (CeAD). We tested the hypothesis of a positive association between AT and Ce...

Abstract Diabetic Kidney Disease (DKD), a serious complication of diabetes mellitus, is a leading cause of end-stage renal disease and a significantly contributes to cardiovascular morbidity. This study investigated the ...

Bipolar depression (BD-D) is both common and incredibly challenging to treat. Even treated individuals with BD-D experience depression approximately 19% of the time, and subsyndromal depression an additional 18%. This st...