Buscar recursos académicos

ABSTRACT Proton exchange membrane water electrolysis (PEMWE) is a compelling route for sustainable green hydrogen production. Yet Ir‐based oxygen evolution reaction (OER) catalysts suffer from a persistent trade‐off ...

Vascular calcification arises from osteogenic transdifferentiation of vascular smooth muscle cells (VSMC) driven by disordered calcium signaling. Sarcoplasmic/ER calcium ATPase 2 (SERCA2) maintains intracellular calcium ...

ABSTRACT Platelets are crucial to the development of thrombosis and coagulation abnormalities in sepsis, but the mechanisms by which they contribute to these pathological processes are not fully understood. Here, we iden...

Protein misfolding and aggregation into amyloid fibrils (AFs) are critical issues associated with protein stability during food processing and storage, as well as with pathological damage in organisms. Hen egg white lyso...

The tight junction regulates the paracellular passage of solutes and water. It is primarily constituted by the family of claudins which assemble to huge multimers and basically seal the paracellular cleft. Certain claudi...

Developing cost-effective and highly durable electrocatalysts to overcome the sluggish kinetics of the oxygen reduction reaction (ORR) is critical for the promotion of proton exchange membrane fuel cells (PEMFCs). In thi...

Abstract Background Sickle cell retinopathy (SCR) is a well-documented and potentially vision-threatening presentation of sickle cell disease (SCD). In this article, we provide a comprehensive review of the management op...

Background The field of extracellular vesicles (EVs) has advanced considerably in recent years with new findings stemming from technical improvements in their isolation and characterization, expanding their potential as ...

mRNA vaccines emerged as a leading vaccine technology during the COVID-19 pandemic. However, their sustained protective efficacies were limited by relatively short-lived antibody responses and the emergence of SARS-CoV-2...

Ureteral stent-associated urinary tract infections (UTIs) remain a significant clinical challenge, primarily due to bacterial adhesion and biofilm formation. To address this, we engineered a multifunctional antibacterial...

Abstract Background Hyperosmotic shock and the resulting cell volume compression are commonly experienced by organs such as the kidneys, causing rapid formation of hyperosmotic phase separation (HOPS) condensates in the ...

Abstract Ocular neovascular and neurodegenerative diseases, such as diabetic retinopathy and age-related macular degeneration, are characterized by abnormal angiogenesis, vascular leakage, and progressive retinal neurode...

Abstract Background Laccases (LACs) are multicopper oxidases that play vital roles in lignin polymerization, cell wall formation, and various stress responses in plants. Despite their importance, genome-wide investigatio...

Abstract Objective Myelodysplastic syndromes (MDS) are associated with a high risk of progression to leukemia, highlighting the critical need to explore novel therapeutic agents. Based on network pharmacology predicti...

Superionic conductors (SICs) exhibit liquidlike ionic diffusivities while maintaining a periodic crystalline lattice, making them promising candidates for applications in fuel cells, solid-state electrolytes, and thermoe...