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Background: Outer membrane vesicles (OMVs) from Gram-negative bacteria are spherical lipid bilayer nanostructures with diameters of 20 to 250 nm. Porphyromonas gingivalis (P. gingivalis), a keystone periodontal pathogen,...

The acidic cleaning wastewater generated during printed circuit board(PCB) manufacturing contains copper ions(Cu2+) at concentrations of 2-6 g/L. The recovery of these copper ions holds significant importance for promoti...

Abstract Per- and polyfluoroalkyl substances (PFAS) and microplastics (MPs) are certain types of persistent plastic contaminants that are a cause of concern to both the ecosystems and human health. The nanotechnologies o...

Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of kidney cancer; however, first-line therapeutic agents show limited efficacy in patients with advanced disease. Bioactive peptides have emerged as p...

ABSTRACT Platelets are crucial to the development of thrombosis and coagulation abnormalities in sepsis, but the mechanisms by which they contribute to these pathological processes are not fully understood. Here, we iden...

Abstract Endocytosis and intracellular trafficking of plasma membrane (PM)-resident proteins are crucial for regulating their activity and polarized localization. However, the molecular mechanisms underlying these proces...

Abstract Background Hyperosmotic shock and the resulting cell volume compression are commonly experienced by organs such as the kidneys, causing rapid formation of hyperosmotic phase separation (HOPS) condensates in the ...

Abstract Ocular neovascular and neurodegenerative diseases, such as diabetic retinopathy and age-related macular degeneration, are characterized by abnormal angiogenesis, vascular leakage, and progressive retinal neurode...

In this work, we report a class of high surface area biomass derived carbon material- (BCMs) obtained from industrial black tea process waste biomass (TW) as a support for synthesis of the nanoparticulate Pt supported on...

Abstract Objective Myelodysplastic syndromes (MDS) are associated with a high risk of progression to leukemia, highlighting the critical need to explore novel therapeutic agents. Based on network pharmacology predicti...

Abstract Man-made synthetic/manufactured nano-objects (MNOs) are increasingly used in almost every scientific sector, including pharmaceutical, agricultural, food, and drug industries worldwide. Rapid advances in nanotec...

Abstract Hydrogen generation from renewable energy sources allows balancing the intermittent nature of solar and wind power. The chemical energy stored in hydrogen can be efficiently converted back to electricity using f...

Objective: Phosphatase and tensin homolog (PTEN) is a critical regulator of cell proliferation, differentiation, and inflammatory balance. However, its downstream proteomic effects in periodontal ligament stem cells (PDL...

Abstract Selenium (Se) enriched forest-grown ginseng is famous for its high Se content and excellent protein quality, which are necessary for varieties of metabolic processes and play an important role in both ginseng gr...

Exosomes, as key mediators of intercellular communication, play a central regulatory role in cellular physiological and pathological processes through their dynamic interaction with the cytoskeleton. The cytoskeleton is ...

ABSTRACT Cells rely on surface receptors to sense and initiate signalling cascades essential for numerous cellular processes, but engineering of synthetic genetic circuits to sense and rewire receptor activities for user...

ABSTRACT Background Intervertebral disc degeneration (IVDD), a prevalent spinal disorder, is closely associated with abnormal mechanical stress. The nucleus pulposus (NP), annulus fibrosus (AF), and cartilaginous endplat...

Arterial Tortuosity Syndrome (ATS) is a rare autosomal recessive connective tissue disorder caused by mutations in the SLC2A10 gene encoding the glucose transporter GLUT10. GLUT10 deficiency leads to the accumulation of ...

Tesis de licenciatura El gen Gpm6a fue identificado como un gen de respuesta al estrés en animales sometidos a diferentes modelos de estrés crónico. En humanos, diferentes patologías neuropsiquiátricas se han asocia...