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Abstract Background Evaluation of left heart size helps determine disease severity in dogs with myxomatous mitral valve disease (MMVD). Hypothesis/Objectives Determine the ability of radiographic vertebral heart size (VH...

ABSTRACT Background Myxomatous mitral valve disease (MMVD) can cause pulmonary hypertension (PH). Mitral valve repair (MVR) has been described as a surgical treatment option for MMVD, but the benefit of MVR when PH is pr...

Abstract Background The renin‐angiotensin‐aldosterone system (RAAS), when chronically activated, is harmful and RAAS‐suppressive drugs are beneficial in the treatment of congestive heart failure (CHF). Mineralocort...

ABSTRACT Background Outcome‐based cardiac risk stratification schemes are lacking for preclinical myxomatous mitral valve disease (MMVD). The Mitral INsufficiency Echocardiographic (MINE) score was developed as an easy...

Abstract Background Treatment is indicated in dogs with preclinical degenerative mitral valve disease (DMVD) and cardiomegaly (stage B2). This is best diagnosed using echocardiography; however, relying upon this limits a...

ABSTRACT Malondialdehyde (MDA) is a biomarker of oxidative metabolism, released under situations such as the stretching of atrial myocytes, a fact related to the development of chronic mitral valve disease (MVD) in dogs....

Abstract Background Atrial fibrillation (AF) occurs in dogs with myxomatous mitral valve disease (MMVD) as a consequence of left atrial (LA) dilatation, and it affects survival and quality of life. Objectives To evaluate...

Abstract Background The Evaluation of pimobendan in dogs with cardiomegaly caused by preclinical myxomatous mitral valve disease (EPIC) study monitored dogs with myxomatous mitral valve disease (MMVD) as they developed c...

ABSTRACT This study aimed to evaluate the Vasovagal Tone Index (VVTI) at different stages of Myxomatous Mitral Valve Disease (MMVD). A total of 525 electrocardiograms from the period between 2014 and 2023 were analyzed, ...

Abstract Heart failure (HF) is a common disease resulting in high morbidity, mortality, and healthcare costs. An important cause of HF is mitral valve regurgitation (MR), which induces left ventricular remodeling and vol...

Myxomatous mitral valve degeneration (MMVD) is the most common acquired heart disease in small and medium-sized dogs, leading to the development of chronic heart failure. The article summarizes current data (2020–2025)...

Abstract Background The pathophysiology of heart failure involves maladaptive angiotensin peptides (APs) and enzymes, including angiotensin 2 (AT2) and angiotensin converting enzyme (ACE), as well as recently described a...

Abstract Background Angiotensin‐converting enzyme inhibitors (ACEIs) are commonly prescribed in dogs, but the ideal dosage is unknown. Hypothesis/Objectives In dogs with cardiac disease, a dose‐response relationship ...

Abstract Background Cardiac disease in dogs impacts the quality of life (QoL) of their owners, but owners' QoL has not been comprehensively assessed in this population. Objectives To develop, validate, and provide prelim...

Abstract Background The proportion of cats with hypertrophic cardiomyopathy (HCM) that lose systolic anterior motion of the mitral valve (SAM) in the long term is unknown. Hypothesis/Objectives Cats with HCM will lose SA...

Abstract Background The clinical relevance of echocardiographic measurements of right heart size and function in dogs with pulmonary hypertension (PH) is unknown. Objective To determine if echocardiographic measurements ...

Abstract Background Cardiac cachexia, loss of muscle mass associated with congestive heart failure (CHF), is associated with increased morbidity and shorter survival times in people, but an association between cardiac ca...

Abstract Background A variant in the canine phosphodiesterase (PDE) 5A gene (PDE5A:E90K) is associated with decreased concentrations of circulating cyclic guanosine monophosphate (cGMP) and response to PDE5 inhibitor tre...

Abstract A 7‐year‐old male castrated Cavalier King Charles Spaniel was hospitalized for 12 days for treatment of severe congestive heart failure secondary to myxomatous mitral valve disease. During that time, 6 ser...

Abstract Background Myxomatous mitral valve disease (MMVD) is frequently diagnosed in small breed dogs. Pimobendan oral solution has been developed to improve dosing accuracy in small and toy breed dogs. Hypothesis/Objec...

Laurence-Moon-Biedl syndrome (LMBS) is a rare autosomal recessive disease which is characterized by obesity, mental retardation, retinitis pigmentosa, polydactyly and hypogonadism. Here in we discussed a patient with LMB...

En la clínica de pequeños animales es común el hallazgo de patologías cardiovasculares cuya confirmación diagnóstica sólo se logra a través de algunos de los métodos complementarios por imagen disponibles. Dentr...

Materias / palabras clave: aortic valve disease, mitral valve disease, tricuspid valve disease, pulmonary valve disease, structural heart disease, great vessels; Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circul...