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Weiming Hao,1 Ruigao Song,1 Huimin Lv,1 Chunying Song2 1Reproductive Medicine Center, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiy...

Abstract With rapid advances in meat science in recent decades, changes in meat quality during the pre-slaughter phase of muscle growth and the post-slaughter process from muscle to meat have been investigated. Commonly ...

Materias / palabras clave: Medicine; Science: Biology (General): Genetics

Abstract Background Follicular development is a prerequisite for vertebrate reproduction, and it is precisely regulated by complex genomic conformations and regulatory elements. However, the dynamic changes in the intera...

Background: Conventional electrocardiography (ECG) analysis faces a persistent dichotomy: Expert-defined features provide interpretability but are limited in capturing latent high-dimensional patterns, whereas deep learn...

Materias / palabras clave: adaptation; mechanism; multiomic; osmotic adjustment; sustainability

Abstract This review provides an effective strategy for understanding meat flavor. Understanding the taste of meat is essential for improving meat quality, and the taste should be analyzed based on complex chemical resea...

ABSTRACT Mutation‐intolerant genes (MIGs), which are constrained in tumors yet variable in normal tissues, are critical for cancer survival. Herein, we developed miDriver, a computational framework using pancancer‐no...

Background and aims Meat-borne Staphylococcus aureus (S. aureus) remains a leading global foodborne pathogen harbouring novel enterotoxin genes (NEGs) encoding superantigenic toxins with conditionally enhanced pathogenic...

BackgroundAnkylosing spondylitis (AS) is an autoimmune disease. Its exact cause remains unclear. It is generally believed to result from a combination of genetic and environmental factors, as well as immune disorders. Ho...

Soil is a living, finite resource that shapes chemical fate, microbial ecology, nutrient supply, and climate regulation, yet environmental science and policy often treat it as an inert substrate. Approximately one-third ...

Background: Outer membrane vesicles (OMVs) from Gram-negative bacteria are spherical lipid bilayer nanostructures with diameters of 20 to 250 nm. Porphyromonas gingivalis (P. gingivalis), a keystone periodontal pathogen,...

ABSTRACT Background and Aims Familial Mediterranean Fever (FMF) is a monogenic autoinflammatory disease caused by mutations in the MEFV gene, resulting in recurrent inflammatory episodes and a risk of developing amyloido...

Abstract Objective Based on the bidirectional communication mechanism of the gut-brain axis, this study aims to systematically elucidate the interactive pathways between gut microbiota and insomnia, review the research p...

ABSTRACT Peripheral nerve regeneration continues to pose a significant clinical challenge, primarily attributable to the inherently limited regenerative capacity of axons and the intricate inflammatory microenvironment t...

Materias / palabras clave: Computer science; Plug-in; Workflow; Software; Usability; Proteomics; Python (programming language); Data science; Data mining; Human–computer interaction; Programming language; Biology

packages to offer tidy interfaces for data operation and visualization. Other new features include gene set enrichment analysis and comparison of enrichment results from multiple gene lists. We anticipate that clusterPro...

A critical component in the interpretation of systems-level studies is the inference of enriched biological pathways and protein complexes contained within OMICs datasets. Successful analysis requires the integration of ...

Resolving the molecular details of proteome variation in the different tissues and organs of the human body will greatly increase our knowledge of human biology and disease. Here, we present a map of the human tissue pro...

Increasing quantitative data generated from transcriptomics and proteomics require integrative strategies for analysis. Here, we present an R package, clusterProfiler that automates the process of biological-term classif...

Materias / palabras clave: chemometrics, environmental analysis, forensic chemistry, omics, pharmaceutical analysis, biomedical analysis; Science: Chemistry: Analytical chemistry

Materias / palabras clave: genomics, proteomics, epigenomics, metabolomics, lipidomics, microbiomics; Medicine; Science: Biology (General): Genetics

Materias / palabras clave: metagenomics, bioinformatics, microbiome, meta-omics methods; Technology: Chemical technology: Biotechnology; Science: Biology (General): Genetics; Medicine

Materias / palabras clave: disease-specific biomarkers, omics science, bioinformatics, applied immunology, molecular medicine; Medicine: Medicine (General)