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Abstract Background The reuse of health data is critical for advancing health research, yet it raises complex ethical, legal, and societal challenges. In the European Union, the recently adopted European Health Data Spac...

Abstract Background Disruption of cellular proteostasis leads to the accumulation and persistence of pathogenic proteins that drive oncogenesis. Key oncogenic and tumor suppressor proteins are frequently dysregulated in ...

ObjectivesThis study aims to delineate the research landscape and evolutionary trajectory of the GLIM criteria in oncology. By mapping development from initial diagnosis to emerging frontiers, it identifies research hots...

With the rapid growth of electronic health records, medical imaging, and high-throughput omics data, precision oncology faces increasing demands for cross-modal information integration and complex clinical decision suppo...

Abstract Background The ageing and growing population, rising cancer rate, and increased healthcare demand drive higher medical costs. Integrating Artificial Intelligence (AI) into oncology revolutionizes cancer diagnosi...

ABSTRACT The growing interest in transferring therapeutic advances from human to veterinary medicine has spurred research into monoclonal antibodies and advanced therapies for treating cancer in small animals. This syste...

The use of timelines is well-established in qualitative research and has been employed across a range of studies. However, the development of timelines (timelining) during interviews on shared decision making (SDM) remai...

Abstract Background The purpose of this article is to present the Brazilian Physical Activity (PA) During Cancer Treatment Guidelines(PA) during cancer treatment, and discuss the adaptations made to align the recommendat...

Abstract Background Apoptosis is a fundamental biological process and a central determinant of therapeutic response in breast cancer (BC). Resistance to immunotherapy is increasingly recognized to be driven, in part, by ...

Resumen: El aumento sostenido de la carga global de cáncer, con proyecciones que superan los 35 millones de casos nuevos hacia 2050, junto con la creciente complejidad de los tratamientos oncológicos, ha posicionado al...

PurposeGlobally, colorectal cancer (CRC) stands as the third most common type of cancer, a ranking that has remained consistent over recent years. However, the scenario diverges in Saudi Arabia, where CRC ascends to the ...

BackgroundImmune checkpoint inhibitors (ICIs) have markedly improved outcomes in metastatic microsatellite instability-high (MSI-H) or deficient mismatch repair (dMMR) gastrointestinal (GI) malignancies. However, in frag...

Background and purpose: Deviations in radiotherapy quality can significantly affect clinical trial outcomes, including overall survival. Radiotherapy quality assurance (RTQA) is a systematic process by which a RT plan is...

Abstract Background Medical oncology is a young specialty in Romania, where early-career oncologists face challenges related to training, mentorship, and research. This study explored their professional status and needs ...

Background and AimsAcquired immunodeficiency in patients with hematological oncology is a serious and common complication, significantly impacting prognosis and quality of life. High doses of cytostatic drugs and the mal...

Abstract Insulin resistance (IR) has emerged as a metabolically relevant contributor to the development and progression of breast cancer (BC), with a case fatality of nearly 15%. IR mainly shows a relationship with obesi...

Abstract Among the epidermal growth factor receptor tyrosine kinases (EGFR) family, HER3 (Human epidermal growth factor receptor3) stands apart due to its minimal inherent intracellular kinase function. Its kinase domain...

Mustafa Şahin,1 Tufan Arslanca2 1Department of Gynecologic Oncology, Konya City Hospital, Konya, Türkiye; 2Department of Gynecologic Oncology, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research H...

Background Cancer is a major cause of mortality and morbidity in Europe, with increasing focus on integrating digital health tools to ensure safe, patient-centred, and equitable oncology care. However, gaps in digital he...

Xiaoying Quan, Lei Lei, Xiaoyan Chen, Xiaoli Jia, Chunzhi Wu, Bin Ye, Qiyue Huang, Min Luo, Ning Wang, Jiayang Yu, Lifu Feng Department of Medical Oncology, the Sixth People’s Hospital of Chengdu, Chengdu, Sichuan, 610...

Abstract Background A core tenet of implementation science is early planning for implementation with invested partners. For health systems, aligning workflows and strategies to the local context and ensuring that the int...