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ABSTRACT: Introduction and aims: To provide the research progress on the cGAS-STING signalling pathway and its related roles in various oral diseases. Methods: We reviewed the recent research on cGAS-STING in PubMed. Th...

Objectives: To comprehensively analyse the burden of five oral diseases in China, including caries of deciduous teeth, caries of permanent teeth, periodontal diseases, edentulism, and other oral disorders; compare their ...

Introduction: The advancement of AI-assisted oral disease diagnosis critically relies on the availability of annotated, high-quality datasets and resilient deep learning architectures. Nevertheless, progress in this doma...

Abstract This study introduces a SMARTphone-based, expert annotated dataset of Oral Mucosa images (SMART-OM), collected to facilitate the development of Artificial Intelligence and Machine Learning (AI/ML) technologies f...

Materias / palabras clave: Dentistry; Oral and dental medicine; Pathology; Diseases; Odontología; medicina oral y dental; Patología; Enfermedades

Introduction and Aims: Evidence suggests a relationship between oral microbiota and cardiovascular diseases (CVDs). However, the roles of specific microbiota in the pathogenesis of CVDs remain underexplored. Methods: Two...

Nonvalvular atrial fibrillation is the most prevalent sustained arrhythmia in chronic kidney disease patients. When compared to warfarin, new oral anticoagulants are found to be non-inferior or superior in safety and eff...

Abstract Scavenging excess reactive oxygen species (ROS) and positively improving intestinal dysbiosis is a promising therapeutic strategy for alleviating inflammatory bowel disease (IBD). However, conventional clinical ...

IntroductionEpidermolysis bullosa (EB) is a rare genetic disease with skin and mucosal fragility. Severe cases present major physical and psychological compromise, contributing to comorbidities and reducing oral health-r...

BackgroundTransforming growth factor-β1 (TGF-β1) contributes to more severe pulmonary disease in people with cystic fibrosis (pwCF). Our preclinical in vitro and in vivo studies demonstrated that losartan could reverse...

Abstract Probiotics are functional microorganisms that exhibit various biological activities, such as allergic reactions, inflammation, and aging. The aim of this study is to evaluate the effects of Bifidobacterium lacti...

Biologic therapeutics have transformed the treatment of chronic and life-threatening diseases, yet their clinical use depends almost entirely on parenteral administration. Oral delivery is the preferred route for patient...

BackgroundCoronary heart disease (CHD) frequently coexists with diabetes mellitus (DM), resulting in a complex metabolic–vascular disorder with poor cardiovascular prognosis. Oral Chinese patent medicines (OCPMs) are w...

Abstract Background Children with congenital and acquired heart disease (CAHD) are at high risk for venous thromboembolism (VTE). Traditional anticoagulants such as vitamin K antagonists (VKAs) and low-molecular-weight h...

Newcastle Disease (ND) threatens poultry productivity worldwide. Vaccination remains central to control, but conventional oral delivery often yields short-lived immunity. Mucoadhesive systems are an alternative delivery ...

Oral pigmentation refers to a pigmented lesion on the oral mucosa, caused by one or more pigments that accumulate, resulting in tissue color change. Pigment lesions can vary in size, color, and location, and may range fr...

ABSTRACT: Background: Lip and oral cavity cancer (LOCC) remains a significant issue in Europe, with an uneven public health burden. While trends have shifted, regional and sex-specific disparities persist due to modifia...

Oral mucosal ageing represents a fundamental reprogramming of the tissue microenvironment, a dynamic process that underlies the functional decline and heightened disease susceptibility observed in the elderly. This revie...

Background: Carbon footprint quantification currently stands as the most accepted model for assessing the ecological impact of human activities.Selecting the most environmentally friendly treatment for pathologies arisin...

Background: Crohn’s disease (CD) and ulcerative colitis (UC) are the two major relapsing conditions of inflammatory bowel diseases. Case Report: A case of Crohn’s disease with orofacial manifestations in a 10 year ol...

Oral lesion’s profi le in autoimmune disease. Oral lesions are commonly found in patients with autoimmune diseases as manifestations of the disease or a side effect of the treatment. Oral lesions must be handled proper...

Chemical composition, antimicrobial and cytotoxic activities of commercial essential oils’ samples from the aerial plant parts of H. officinalis, R. officinalis and S. officinalis were investigated. Analyses by GC-FID ...

BackgroundPoor oral health is associated with cardiovascular diseases (CVDs), largely due to shared risk factors such as smoking, diabetes and socioeconomic disadvantage. Integrating oral health into primary and speciali...

ABSTRACT Background and Aims People with mental health disorders experience disproportionately poor oral health and face persistent barriers to maintaining oral hygiene. This study aimed to assess the feasibility of supp...