Buscar recursos académicos

The purpose of this study was to attain and characterize ternary complexes of simvastatin, β-cyclodextrin (βCD) and different polymers, and then select those that lead to a greater increase in drug solubility. The comp...

When polymers are irradiated with heavy ions new chemical groups are created in a few microns of the material. The irradiation changed the polarity and wettability on the surface so that could enhance the biocompatibilit...

Neste estudo, comprimidos matriciais de captopril foram desenvolvidos utilizando-se hidroxipropilmetilcelulose (HPMC) e quitosana (QTS) em diferentes proporções (50:50, 60:40, 40:60, 20:80), por compressão direta. Os ...

A biphasic gastroretentive drug delivery system of acyclovir consisted of loading dose tablet and floating multiple matrix tablets was prepared by direct compression process. The delivery system was designed by hydroxy...

The present study evaluated novel polymer mixtures prepared by spray drying of an aqueous dispersion of moth bean starch with Carbopol 934P and HPMC K4M for to be used as platform for peroral mucoadhesive drug delivery...

The aim of the present study is to prepare bilayered floating tablets of diltiazem with different ratios of polymers like HPMC K4M, carbopol 934 P, sodium alginate, Plantago ovata seed husk (psyllium) and to carry out ev...

The aim of the present investigation is to improve the dissolution of poorly water soluble drug valsartan by preparing solid dispersions and also to evaluate the effect of different inert carriers on flow properties of s...

Nimesulide was formulated as novel dual coated microparticles using chitosan (CTN) and ethyl cellulose (EC) as encapsulating materials for its improved delivery to the intestine and to prevent gastric irritation and incr...

Implants prepared with polymer blends [poly (e-caprolactone)-poly(lactide), PCL-PLA] at different rates were developed from microspheres. Approximately 19% of dexamethasone acetate was encapsulated into the microsphere...

The aim of the present study was to develop a sustained release mucoadhesive buccal film of naproxen, which can be used to treat the inflammation in the oral cavity. The mucoadhesive buccal films were prepared by solve...

Las semillas de Cucurbita pepo L., por su elevado porcentaje de aceite fijo, son ricas en ácidos grasos poliinsaturados, fitoesteroles, tocoferoles y carotenoides, empleándose tradicionalmente como antiinflamatorio en ...

Transdermal drug delivery systems of venlafaxine hydrochloride were prepared by using combination of hydrophilic (HPMC E15) and hydrophobic (ERS100 and ERL 100) polymers in 1:5, 2:4, 3:3, 4:2, 5:1 ratios by solvent casti...