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The aim of this study was to validate an agar diffusion method through the parameters linearity, precision and accuracy, to quantify apramycin in soluble powder. The calibration curve of apramycin was constructed by plo...

The quality control of herbal drugs and their intermediates is essential, especially when they are used as feedstock for medicine development. This study aimed at applying the methodologies established by Brazilian legis...

Raman spectroscopy in combination with partial least-squares (PLS) regression method was developed for sulphamethoxazole (SMZ) and trimethoprim (TMP) simultaneous determination in powder mixtures. The calibration set was...

The great variety of excipients to which we have access thanks the globalization gives rise to the necessity to evaluate their functionality, currently the pharmaceutical performance of croscarmellose and carmacel as tab...

Spherical crystallization (SC) is a promising alternative for improiving micromeritic properties and dissolution rate of active pharmaceutical ingredients. In the present work spherical agglomerates of carvedilol (CAR) w...