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Purpose: To investigate the prospects for prevention of type 1 diabetes mellitus (T1DM) through vitamin D supplementation in risk groups. Material/Methods: A targeted review of the scientific literature by keywords in t...

Abstract Background Prophylactic medications are commonly used to prevent tuberculosis and opportunistic infections in people living with HIV (PLWH) who are on first-line antiretroviral therapy (ART). However, their cumu...

BackgroundCatheter-related thrombosis (CRT) is a common complication following central venous catheter (CVC) placement in patients with cancer, increasing mortality and adverse outcomes. However, robust evidence on optim...

Daniele Focosi,1 Massimo Franchini,2 Arturo Casadevall3 1North-Western Tuscany Blood Bank, Pisa University Hospital, Pisa, Italy; 2Department of Transfusion Medicine and Hematology, Carlo Poma Hospital, Mantua, Italy; 3D...

Background: Pre-exposure prophylaxis (PrEP) guideline implementation varies widely across countries as a result of differences in health systems, resources, and HIV priorities. Since 2016, oral PrEP has been available t...

Animal-bite and scratch visits to the emergency department (ED) often require time-sensitive decisions on rabies post-exposure prophylaxis (PEP) alongside tetanus prevention. In China, recent national standards and local...

Abstract Background Hereditary angioedema (HAE) is a rare, potentially life-threatening genetic disorder that is caused by C1-inhibitor (C1INH) deficiency or dysfunction. This scoping review sought to map recent advances...

Abstract Background Cerebral toxoplasmosis is a rare but potentially fatal opportunistic infection in non-HIV immunocompromised patients, particularly after allogeneic hematopoietic stem cell transplantation (allo-HSCT)....

Central nervous system (CNS) involvement by CLL is rare. We report a non-treated CLL patient with low-risk factors, but showed leptomeningeal involvement during/after neuroborreliosis and EBV meningitis. An 80-year-old w...

Emily Kutrieb,1 Derek Weycker,1 Montserrat Vera-Llonch,2 Arthur Zbrozek,3 Kevin Ottino,1 William R Lumry4 1Avalere Health, Washington, DC, USA; 2Ionis Pharmaceuticals, Boston, MA, USA; 3Ionis Pharmaceuticals, Carlsbad, C...

Background: Octocog alfa and rurioctocog alfa pegol have demonstrated efficacy in the prevention and management of bleeding associated with hemophilia A (HA) in clinical trials. The German AHEAD study (DRKS00000556) was ...

Abstract Introduction Respiratory syncytial virus (RSV) is the leading cause of respiratory infections and hospitalization among infants and a major burden on pediatric emergency department (EDs). Nirsevimab has recently...

Abstract Objective Voriconazole is a commonly used antifungal medication, particularly for treating invasive pulmonary aspergillosis and as prophylaxis in hematologic malignancies. However, it can cause adverse effects, ...

Abstract Background The inability of antiretroviral medications to inhibit HIV is known as antiretroviral treatment failure. One of the greatest problems facing HIV patients receiving antiretroviral therapy is treatment ...

Abstract Background Pancreatic portal hypertension (PPH) is a distinct form of sinistral (left-sided) portal hypertension, primarily resulting from pancreatic diseases such as acute or chronic pancreatitis and pancreatic...

Needlestick injuries (NSI) result from penetrating trauma or lacerations to the skin. This includes needles, cannulae, needles utilized for connecting components of intravenous administration systems, and surgical equipm...

Abstract Women with inherited thrombophilia represent more than 15% of the pregnant population. 20–50% of pregnancy-related venous thromboembolism (VTE) is associated with at least one inherited thrombophilia, which in...

Abstract This update to the 2019 Canadian Hereditary Angioedema (HAE) Guideline broadens its focus to include the management of patients with HAE worldwide, building on its established international framework. It has bee...

Abstract Background Hematopoietic stem cell transplantation (HSCT) is an effective treatment for refractory or relapsed acute lymphoblastic leukemia (ALL). However, persistent challenges, such as post-transplant relapse ...