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El objetivo de este trabajo fue estudiar el impacto de la incompatibilidad/compatibilidad termodinámica entre las proteínas del lactosuero y diferentes hidroxipropilmetilcelulosas, sobre las transiciones térmicas de l...

Materias / palabras clave: Engineering technology.; Cuba.; Chemistry.; Ingeniería Quíimica.; Ingenieria Quimica.

Materias / palabras clave: microbial structure, process and products, industrial microorganisms, microbial enzymes, enzymology and protein engineering, healthcare products; Science: Microbiology

Materias / palabras clave: enviromental microbiology, translational research, applied microbiology, industrial microbiology, protein engineering, synthetic biology; Science: Biology (General)

Materias / palabras clave: synthetic biology, protein engineering, gene synthesis, gene optimization, viral engineering, genetic systems; Science: Biology (General) | Technology: Chemical technology: Biotechnology

Materias / palabras clave: amino acid metabolism, protein synthesis, peptide engineering, therapeutic applications, biotechnological applications, nutritional aspects; Science: Chemistry: Organic chemistry: Biochemistry | Science: Biology (General...

Materias / palabras clave: protein folding, immunochemistry, drug targeting, biochemistry, biophysics, genetic engineering; Science: Chemistry: Organic chemistry: Biochemistry

Copper sites in proteins are designed to perform either electron transfer or redox catalysis. Type 1 and CuA sites are electron transfer hubs bound to a rigid protein fold that prevents binding of exogenous ligands and s...

Abstract Background Chinese hamster ovary (CHO) cells are pivotal in biopharmaceutical production, yet balancing high recombinant protein yield with cell survival remains challenging. While previous studies have targeted...

3D printing has emerged as vanguard technique of biofabrication to assemble cells, biomaterials and biomolecules in a spatially controlled manner to reproduce native tissues. In this work, gelatin methacrylate (GelMA)/al...

Abstract The systematic exploration of novel bioactive compounds with superior functional properties is critical for driving innovations in agriculture, healthcare, and related fields, thereby becoming essential for adva...

Polyelectrolyte multilayers (PEMs) based on biopolyelectrolytes are highly appealing for the surface engineering of biomaterials and the tuning of cell response and phenotypes for biomedical applications. However, cell a...

Abstract Using biomedical foundation models (FMs) for inference on small cohorts, represents a promising and practical route to advance drug response biomarker discovery and target identification. Here, we demonstrate th...

IntroductionPolygonum multiflorum (PM), a traditional medicinal herb, is renowned for its regenerative effects on hair growth; however, its therapeutic application has been largely confined to crude extracts. Recent adva...

Background: The bacterial chromosome may be used to stably maintain foreign DNA in the mega-base range. Integration into the chromosome circumvents issues such as plasmid replication, stability, incompatibility, and copy...

Protein aggregation plays a central role in the pathogenesis of many neurodegenerative diseases and poses major challenges in protein engineering. A key driver of this process is the presence of aggregation-prone regions...

Biofabricated scaffolds facilitate bona fide cellular interactions, cell type specification, and the formation of three-dimensional tissue architecture from human pluripotent stem cells (hPSCs). However, xenogenic biomat...

ABSTRACT The elastic cartilage is composed by chondroblasts and chondrocytes, extracellular matrix and surrounded by perichondrium. It has a low regeneration capacity and is a challenge in surgical repair. One of obstacl...

ABSTRACT The bacterial flagellar filament acts as a propeller to drive most bacterial swimming. The filament is made of flagellin, known as FliC in Escherichia coli. FliC consists of four domains, the highly conserved co...

A field experiment was carried out in summer season 2024  at one field  of the Agricultural Engineering Sciences College, University of Baghdad, in order to study the impact of organic and phosphate fertilization plus ...