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Abstract Background Covalent protein modification by drugs or their reactive metabolites has emerged as an important mechanism underlying pharmacological activity. However, its contribution to the therapeutic effects of ...

ABSTRACT Background The muscle tissue of dairy cows is a site of β‐hydroxybutyrate (BHBA) metabolism. The mechanisms underlying the changes in proteins and metabolites in the muscle tissue of cows with ketosis remain ...

Abstract Glaucoma trabecular meshwork (GTM) cells cultured in vitro retain many characteristics of their in situ phenotype. Here, we used isobaric tandem mass tags (TMTpro) to label peptides from glaucomatous and non-gla...

Abstract Black rhinoceros are critically endangered due to poaching in the wild (in situ). Globally, fewer than 200 animals are maintained as an ex situ insurance population. Unfortunately, the ex situ population faces m...

Abstract Background Proteins represent the dynamic downstream products of genes, and have the potential to substantially increase understanding of the complexities of cancer biology. Undifferentiated pleomorphic sarcoma ...

BackgroundCancer cell evasion of the immune response is critical to cancer development and metastases. Clinicians' ability to kickstart the immune system to target these rogue cells is an ever-growing area of research an...

The present study presents the first characterization of a full cytohesin-2 knockout and establishes cytohesin-2 as a critical factor for perinatal development, identifying a previously unrecognized role of cytohesin-2 i...

Intrauterine growth restriction is described as a fetus not reaching its growth potential during pregnancy. Placental malperfusion is the main cause of Intrauterine growth restriction . Management of Intrauterine Gowth ...

Abstract Background Genetic aberrations are among the critical driving factors of lung cancer. Importantly, the impact of genetic variations on proteomic dysregulations with the goal of characterizing potential diagnosti...

Abstract Background Proteins and RNA circulate in plasma and can offer insights into human physiology. Yet, despite their clinical importance, direct comparisons between these analytes remain unexplored. Methods: Here, w...

Abstract A macroscopic perspective is indispensable for understanding the intricate relationship between deubiquitinases and tumorigenesis. Proteomics has been proposed as a viable approach for elucidating the complex ro...

Part I: Molecular Biology of Cancer Molecular Methods in Oncology Section 1. Amplification Techniques Section 2. RNA Interference Section 3. cDNA arrays Section 4. Tissue arrays Section 5. Cytogenetics Section 6. Bioinfo...

The 11th edition of the Manual of Clinical Microbiology continues to set the standard for state-of-the-science laboratory practices as the most authoritative reference in the field of clinical microbiology. This new edit...

Materias / palabras clave: genomics, proteomics, epigenomics, metabolomics, lipidomics, microbiomics; Medicine; Science: Biology (General): Genetics

Materias / palabras clave: translational proteomics, molecular medicine; Medicine

Materias / palabras clave: genomics, proteomics, bioinformatics, epigenomics; Science: Biology (General); Medicine: Medicine (General): Computer applications to medicine. Medical informatics

Materias / palabras clave: vaccines, microbiology, infectious diseases, immunology, proteomics; Medicine: Internal medicine: Infectious and parasitic diseases

Materias / palabras clave: precision medicine, general medicine, genomics, proteomics; Medicine

Materias / palabras clave: functional genomics, epigenomics, proteomics, pharmacogenomics; Medicine: Internal medicine; Science: Biology (General): Genetics

Materias / palabras clave: biomedical sciences, life sciences, genomics, transcriptomics, proteomics, omics; Medicine; Science: Biology (General)

Materias / palabras clave: genomics, proteomics, transcriptomics, epigenetics, bioinformatics; Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Biology (General): Genetics

Materias / palabras clave: pharmacokinetics, pharmacoepidemiology, personalized therapy, molecular screening with the use of modern methods of proteomics, modeling abnormalities in laboratory animals; Medicine: Therapeutics. Pharmacology