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Abstract Introduction There is evidence that the coronavirus disease 2019 (COVID-19) pandemic impacted students on health care courses, including evidence of associations between anxiety or depression and inadequate co...

Objectives: Psychiatric disorders are frequently found in both patients with PNES and DRE, making the differential diagnosis even more complex. The aim of this study was to analyze and compare psychiatric aspects and the...

BackgroundTraumatic brain injury (TBI) with post-traumatic stress disorder (PTSD) is treatment-resistant, with conventional psychotherapy showing limited efficacy due to neurocognitive impairments.Case SummaryWe report t...

Christos Kleisiaris,1 Theodora Arida,2 Maria Klesiora,1 Konstantinos Tsaras,1 Maria Malliarou,1 Ioanna V Papathanasiou,1 Theodosios Paralikas,1 Nikolaos Bakalis,3 Mahmoud Ogla Al-Hussami,4 Wafa Hamad Almegewly,5 Savvato ...

Chronic psychosocial stress is a major risk factor for anxiety, depression and related disorders, yet a hypothalamic-pituitary-adrenal (HPA) axis centric framework alone is insufficient to explain stress-induced vulnerab...

Background The importance of psychosocial functioning in the assessment, diagnosis and treatment of major depressive disorder (MDD) is widely recognised. However, there is a lack of effective scales to assess psychosocia...

Tinghan Fu,1– 3,* QianQian Wang,1– 3,* Shasha Chen,1– 3,* Tiannan Xu,1– 3 Hongye Wu,1– 3 Ruimei Ni,1– 3 Kai Zhang2– 4 1School of Mental Health and Psychological Science, Anhui Medica...

Abstract Background Generative artificial intelligence (AI) chatbots are being increasingly adopted by adolescents to address mental health–related concerns, such as seeking emotional reassurance, clarifying symptoms, ...

Abstract Thalamocortical circuits regulate information flow between sensory inputs and higher-order processing, and their disruption is increasingly implicated in psychotic disorders. However, scalable biomarkers of this...

BackgroundAttention deficit/hyperactivity disorder (ADHD) is characterized as a neurodevelopmental disorder onset in childhood. However, accumulating evidence suggests that some adults may fulfill current diagnostic crit...

BackgroundDepressive disorders are clinically heterogeneous and mechanistically complex psychiatric conditions. Transcranial direct current stimulation (tDCS), a key non-invasive neuromodulation technique, has expanded r...

Immunophilins are a family of proteins whose signature domain is the peptidylprolylisomerase domain. High molecular weight immunophilins are characterized by the additional presence of tetratricopeptide-repeats (TPR) thr...

Introduction Paediatric anxiety disorders are among the most common psychiatric disorders of childhood and adolescence, affecting between 15% and 30% of youth. Rates rose sharply during the COVID-19 pandemic, and untreat...

Background and Aims: Autism in children is known to affect brain systems implicated in cognitive, communication, social functioning and intelligence. Although autism is a neurobiological disorder, behavioral interventi...

INTRODUCTION: This study aimed to investigate serum levels of proline, prolidase, proline dehydrogenase (PRODH), and reactive oxygen species (ROS) in patients with schizophrenia and healthy controls, to evaluate potentia...

Abstract Melatonin plays a key role in circadian regulation, and its interaction with the gut microbiota may be critical for early-life development. Beyond its circadian function, melatonin dysregulation is implicated in...

Abstract Background Migraine is a very common chronic neurological disorder associated with severe disability and significant social burden worldwide. Beyond recurrent headache attacks, increasing evidence indicates that...

El concepto de reserva cerebral y cognitiva (RCC) fue establecido con el objeto de explicar por qué y cómo ciertos individuos, pese a estar afectados por una patología cerebral, no expresan las alteraciones cognitivas...

Introduction: Olfactory Reference Syndrome (ORS) is a rare, under-recognized, and understudied psychiatric condition characterized by a persistent belief about the perceived odor, ideas of reference, and engagement in re...

Abstract Eating disorders (ED) are a group of potentially severe mental disorders characterized by abnormal energy balance, cognitive dysfunction, and emotional distress. Cognitive inflexibility is a major challenge to s...

Ahmad H Almadani,1,2 Ayedh H Alghamdi,1,2 Falwah S Alsalman,3 Abdullah J Alghanim,4 Refan T Hashim,2 Abdulrahman I Binbakhit,5 Aleen A Alkulyah,5 Reema M Almutairi,5 Laila A Alfarhan,5 Abdullah K Muhnna,5 Malak M Aldakhi...

Abstract Introduction Sexual dysfunction is common in individuals with psychiatric disorders and under psychotropic medication such as antidepressants and antipsychotics. Several scales have been developed to assess sex...

This article highlights the relevance of the humanities to psychiatric discussions. It considers Thomas De Quincey’s autobiographical Confessions of an English Opium-Eater (1821), where the author charts his opium expe...