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Abstract Background Ureteral double-J (JJ) stents are widely used in endourological practice but are frequently associated with discomfort and stent-related morbidity, particularly during removal. Extraction-string stent...

In this paper we raise the question “why is agreement so common across natural languages?”. We will argue that the challenge of grammar inference in natural and artificial languages provides key insights into the ubi...

Abstract Background Head and neck squamous cell carcinoma (HNSCC) is a prevalent and aggressive malignancy with limited prognostic markers. Ubiquitin-specific peptidase 33 (USP33) has emerged as a potential modulator of ...

INTRODUCTION: With the deepening of China's "Dual Carbon" goals, the scale of photovoltaic (PV) installations continues to expand, placing stringent requirements on the accuracy, scenario adaptability, and robustness of ...

BackgroundWorkplace violence (WPV) against physicians represents an escalating global concern, with significant implications for India. This phenomenon substantially undermines the mental health, professional morale, and...

This paper proposes a dual-spectrum communication strategy for Industrial Internet of Things (IIoT) scenarios that integrates visible light communication (VLC) and ultraviolet communication (UVC). In the proposed approac...

Abstract Generative deep learning models have demonstrated significant potential in designing drug-like molecules. However, medicinal chemistry typically requires generating analogues that combine structural similarity w...

Background: The modern intrauterine contraceptive device (IUCD) is a highly effective, safe, private, long-acting, coitus-independent, and rapidly reversible method of contraception with few side methods of contraception...

Background: Cardiac complications arising from diabetes mellitus manifest as structural and functional myocardial alterations independent of traditional cardiovascular risk factors. The intricate molecular underpinnings ...

Abstract With the increasing performance requirements for data acquisition in applications such as the Internet of things and artificial intelligence, analog-to-digital converters (ADCs) face stringent trade-offs among s...

Artificial intelligence (AI) is increasingly used to design and optimize small molecules. However, most current workflows remain centered on drug-candidate objectives, such as potency, ADMET, and drug-likeness, rather th...

Objective Endometriosis (EMs) is a chronic gynaecological condition characterised by the ectopic growth of endometrial tissue; however, its molecular mechanisms remain insufficiently understood. Ferroptosis, an iron-depe...

Determining the quantum-classical boundary between quantum circuits that can be efficiently simulated classically and those that cannot remains a fundamental question. One approach to classical simulation is to represent...

Immune checkpoint inhibitors (ICIs) have been game changer in cancer therapy but can trigger diverse immune-related adverse events (irAEs) that impact multiple organs. This review offers a unified perspective on irAE ris...

Context. Co-orbital objects, also known as Trojans, are celestial bodies that share a 1:1 mean motion resonance orbit with a planet. Many planets in our Solar System hold Trojans, yet none has been confirmed in exoplanet...

BackgroundResting metabolic rate (RMR) prediction equations used today often rely on the consideration of binary sex. Significant intrasex variability and a lack of data on diverse populations raise concerns about these ...

Abstract Infectious disease diagnostics has been transformed by metagenomic next‐generation sequencing (mNGS), an unbiased approach that detects bacteria, viruses, fungi, and parasites in a single assay. By sequencing ...

Abstract Land subsidence induced by underground coal mining consistently leads to persistent ponding in coal-grain overlapping areas (COAs), substantially impairing agricultural productivity. However, amid stringent farm...

Abstract Background Breast cancer prognosis is the result of complex interactions between tumor biology, treatment, and host factors. While germline genetic variation is increasingly incorporated into breast cancer risk ...

Abstract Esophageal cancer (EC) is a malignant tumor characterized by high incidence and mortality, and its complex pathogenesis necessitates the development of effective therapeutic strategies. In this study, we investi...

Background: Barrett's esophagus (BE) represents a critical precancerous lesion arising from chronic gastroesophageal reflux disease (GERD), with significant risk of progression to esophageal adenocarcinoma. Despite advan...

Abstract We explore a cosmological framework in which a Gauss–Bonnet (GB) coupled scalar field, acting as dark energy, interacts with a fermionic dark matter field through a coupling obtained from the point of view of ...

Abstrak Penelitian ini menganalisis ketidaklengkapan norma dalam Undang-Undang Nomor 2 Tahun 2014 tentang Jabatan Notaris (UUJN) terkait ketiadaan pengaturan eksplisit mengenai kewenangan notaris dalam penyimpanan ser...

Abstract Objective Myelodysplastic syndromes (MDS) are associated with a high risk of progression to leukemia, highlighting the critical need to explore novel therapeutic agents. Based on network pharmacology predicti...