Buscar recursos académicos

Extreme indoor and outdoor conditions in patients’ places of stay (hot or cold air and changes in humidity) lead to weakening of the lipid barrier function and disproportionate epidermal microbiota which results in a l...

ABSTRACT Background and Aims The present review aims to ascertain whether reproductive disorders are associated with specific physical, mental, personality, and social traits. This information may be used to support or r...

Materias / palabras clave: hypomelanosis of ito; pigmentary disorders; mosaicism

Immune dysregulation can lead to autoimmunity and autoinflammation. The goal of treatment is to balance targeted therapies while avoiding infections or other side effects, which becomes complicated with multiple diagnose...

Background Tranexamic acid (TXA) is widely used for pigmentary disorders, but its anti-ageing potential remains unclear. This study aimed to evaluate whether topical 3% TXA improves early periorbital wrinkles in women wi...

Lichen sclerosus is a chronic inflammatory skin disorder that primarily affects the anogenital region, but can also present in extragenital areas. In children, lichen sclerosus most commonly involves the vulvar and peri...

Abstract Background Skin disorders are widespread, and there is increasing demand for reliable, standardized herbal therapeutics. Kumkumadi Tailam, a classical Ayurvedic polyherbal oil formulation, incorporates several b...

IntroductionChronic spontaneous urticaria (CSU) is a clinical diagnosis managed according to American Academy of Allergy, Asthma & Immunology (AAAAI) and the American College of Allergy, Asthma & Immunology (ACAAI) guide...

Thymic stromal cells drive T cell development by supplying key cues for progenitor proliferation and differentiation. Although thymic epithelial cells are well characterized, recent studies highlight crucial functions of...

Abstract Purpose Cri-du-chat syndrome (OMIM 123450) is caused by a deletion of the short arm of chromosome 5 and characterized by a distinct high-pitched cry, developmental delay/intellectual disability, and various dysm...

Haematohidrosis is an exceptionally rare and poorly understood clinical phenomenon characterized by the spontaneous excretion of blood through intact skin or natural orifices, with episodes often reported in association ...

Aim. The aim of this study was to review the current scientific literature on the adverse effects of anabolic-androgenic steroids (AAS) use in physically active men and to highlight the need for further research in this ...

IntroductionOSMR encodes oncostatin M receptor beta (OSMRβ), a cell surface receptor of the gp130 family that binds OSM and IL-31, and is highly expressed on fibroblasts. The gp130 family comprises signaling proteins, m...

BackgroundNewborn screening for severe combined immunodeficiency (SCID) using T cell receptor excision circles (TRECs) enables early detection of disorders affecting T cell development. While low TRECs typically indicate...

BackgroundTelomere biology disorders (TBD) are rare multisystem disorders characterized by a wide array of clinical presentations, including bone marrow failure, pulmonary fibrosis, and malignancy predisposition due to p...

POEMS syndrome is a rare multisystem disorder characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal protein (M-protein) secretion, and skin changes. Its pathogenesis is driven by plasma cell dyscrasia...

CARMIL2 is a protein required for T cell activation, specifically for CD28 and CARMA-1/PKC coupling and NF-kB signaling. CARMIL2 deficiency has pleiotropic presentations, which can include recurrent viral and mucocutaneo...

Rosacea is a chronic inflammatory skin disorder primarily characterized by persistent facial erythema, episodic flushing, papules and pustules, as well as phymatous changes. Despite extensive research, the pathogenesis o...