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A preoperative nomogram for predicting 2-year postoperative recurrence after percutaneous transforaminal endoscopic decompression in degenerative lumbar spinal stenosis

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A preoperative nomogram for predicting 2-year postoperative recurrence after percutaneous transforaminal endoscopic decompression in degenerative lumbar spinal stenosis

Xinyi Luo et al · Frontiers Media S.A · 2026 · ISSN 2673-8740

Background and objectivesPostoperative recurrence after percutaneous transforaminal endoscopic decompression (PTED) for degenerative lumbar spinal stenosis (DLSS) remains a clinically relevant challenge, complicating pre...

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Circadian regulation in intervertebral disc degeneration: mechanisms and clinical implications

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Circadian regulation in intervertebral disc degeneration: mechanisms and clinical implications

Jiarui Zhao et al · Frontiers Media S.A · 2026 · ISSN 2296-889X

Circadian rhythms are essential for maintaining intervertebral disc (IDD) homeostasis and regulate cellular metabolism, mechanical responses, and therapeutic efficacy. Core clock genes, especially CLOCK and BMAL1, have c...

LCC LCC:Biology (General)Idioma eng

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Mesenchymal Stem Cell-Lysate Sustained-Release Nano-Hydrogel Alleviates Spinal Cord Injury by Inhibiting Ferroptosis and Mitochondrial Intrinsic Apoptosis

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Mesenchymal Stem Cell-Lysate Sustained-Release Nano-Hydrogel Alleviates Spinal Cord Injury by Inhibiting Ferroptosis and Mitochondrial Intrinsic Apoptosis

Ming Lu Sun et al · Elsevier · 2026 · ISSN 0020-6539

Background: Spinal cord injury (SCI) has emerged as a major challenge to global public health due to its low recovery rate and high disability rate, making the development of novel therapeutic approaches imperative. Mese...

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The Role of Piezo 1 in the Study of Intervertebral Disc Degeneration: Phenotype, Mechanism and Treatment

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The Role of Piezo 1 in the Study of Intervertebral Disc Degeneration: Phenotype, Mechanism and Treatment

Guangye Li et al · Wiley · 2026 · ISSN 1757-7853

ABSTRACT Background Intervertebral disc degeneration (IVDD), a prevalent spinal disorder, is closely associated with abnormal mechanical stress. The nucleus pulposus (NP), annulus fibrosus (AF), and cartilaginous endplat...

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Analysis of immune-related alterations in blood and spinal cord of canine degenerative myelopathy, a spontaneous model of amyotrophic lateral sclerosis

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Analysis of immune-related alterations in blood and spinal cord of canine degenerative myelopathy, a spontaneous model of amyotrophic lateral sclerosis

Shunya Yokota et al · Nature Portfolio · 2026 · ISSN 2045-2322

Abstract Canine degenerative myelopathy (DM) is an adult-onset neurodegenerative disease considered a spontaneous model of human amyotrophic lateral sclerosis (ALS). Neuroinflammation occurs in both DM and ALS, and cross...

LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng

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Automated deep-learning quantification of intramuscular fat in lumbar spine muscles on Dixon MRI: validation and normative reference values from 173 healthy adults

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Automated deep-learning quantification of intramuscular fat in lumbar spine muscles on Dixon MRI: validation and normative reference values from 173 healthy adults

Germán Balerdi et al · BMC · 2026 · ISSN 1471-2342

Abstract Background Intramuscular fat (IMF) accumulation in lumbar‑spine muscles is associated with sarcopenia, low‑back pain and poorer surgical outcomes. Dixon MRI allows the measurement of IMF with voxel-wise fat ...

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Clinical and magnetic resonance imaging characterization of cervical spondylomyelopathy in juvenile dogs

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Clinical and magnetic resonance imaging characterization of cervical spondylomyelopathy in juvenile dogs

Marília de AlbuquerqueBonelli et al · Oxford University Press · 2019 · ISSN 0891-6640

Abstract Background Cervical spondylomyelopathy (CSM) occurs because of compression of the cervical spinal cord, nerve roots, or both, usually affecting young adult to older large and giant breed dogs. Juvenile dogs are ...

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Intervertebral disc progenitor cells: roles in regeneration and disease

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Intervertebral disc progenitor cells: roles in regeneration and disease

Pulin Yan et al · BMC · 2026 · ISSN 1757-6512

Abstract Intervertebral disc (IVD) degenerative disease is a prevalent and debilitating spinal disease. Current treatments only focus on symptomatic relief but fail to halt disease progression or restore the native biome...

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Single-cell RNA sequencing uncovers neutrophil clusters associated with autoimmune neuroinflammation

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Single-cell RNA sequencing uncovers neutrophil clusters associated with autoimmune neuroinflammation

Yong Wang et al · BMC · 2026 · ISSN 1742-2094

Abstract Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS) characterized by multifocal inflammation and axonal degeneration, driven by innate and adaptive immune cells. Th...

LCC LCC:Neurology. Diseases of the nervous systemIdioma eng

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Two-dimensional posture evaluation in Parkinson’s disease: effect of loads on the spinal angle during gait

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Two-dimensional posture evaluation in Parkinson’s disease: effect of loads on the spinal angle during gait

Celoria, Paula et al · RI ITBA · 2022

"Parkinson’s Disease patients present diminished coordination caused by neural degeneration. This leads to large motor difficulties during gait such as balance loss and pronounced forward inclination of the upper bod...

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JOR Spine

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JOR Spine

Wiley; United States · ISSN 2572-1143

Materias / palabras clave: spine, orthopaedics, spinal degeneration, spinal cord, biomechanics, spinal development; Medicine: Surgery: Orthopedic surgery

Idioma English

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