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BackgroundItchy E3 ubiquitin ligase deficiency (ITCH deficiency) is a rare monogenic immune dysregulation syndrome characterized by early-onset multisystem autoimmunity and significant morbidity and mortality. Only one p...

Post-transplant cyclophosphamide (PTCy) is increasingly used for graft-versus-host disease (GVHD) prophylaxis in allogeneic hematopoietic stem cell transplantation (alloHCT), across both haploidentical and HLA-matched do...

Objective: Hematopoietic stem cell transplantation (HSCT) is an effective treatment for acute myeloid leukemia (AML) patients, leveraging cytotoxic conditioning regimens and graft-versus-leukemia effects. Reduced-intensi...

ObjectivesPatients with severe aplastic anemia (SAA) complicated by mucormycosis face a significantly elevated risk of mortality and present considerable therapeutic challenges. This study aimed to delineate nursing mana...

Abstract Background Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains a curative option for children with refractory, relapsed, or high-risk acute lymphoblastic leukemia (ALL). Conditioning regimens ...

OBJECTIVE: The aim of this study was to closely follow up renal functions in patients for a period of 100 days after hematopoietic stem cell (HSC) transplantation in order to be able to determine the incidence, possibl...

Key Points. Almyloid light chain amyloid patients post autologous stem cell transplantation with higher eGFR was not associated with better progression-free survival but was associated with increased overall survival (OS...

Materias / palabras clave: Stem cells; Transplantation; Células madre; Trasplante

ABSTRACT Retinal ganglion cell (RGC) degeneration represents a cardinal etiology of irreversible vision loss in glaucoma, where efficacious regenerative therapies remain scarce. RGC replacement therapy holds promise for ...

Mesenchymal stem cells (MSC) transplantation had been shown to have a potential for reducing chronic pain. MSC transplantation suppresses excessive inflammation, and one of the potential mechanisms of action is a gap jun...

Abstract Intracerebral hemorrhage (ICH) is a devastating neurological condition with high mortality and morbidity. Despite advancements in medical and surgical treatments, the long-term prognosis of ICH remains poor. Ste...

ObjectiveRegulatory T cells (Tregs) play an essential role in transplantation immune tolerance. Although CD4+ Tregs have been extensively studied, the contribution of CD8+ regulatory T-cell subsets to transplant toleranc...

Abstract Recent studies have demonstrated that exosome therapy can promote the recovery of ovaries in premature ovarian failure (POF) models, which may aid in fertility restoration. This study aimed to investigate the th...

Abstract Background Acute liver failure (ALF) is a life-threatening syndrome characterized by rapid deterioration of liver function, resulting in high mortality and posing a substantial global health burden. Human embryo...

Kidney diseases, related to high morbidity and mortality, are one of the diseases that should be primarily investigated. Development of acute and chronic kidney diseasesis due to lack of functioning renal repair mechan...

Abstract Neuroinflammation is a key pathogenic factor for neurodegenerative diseases. Mesenchymal stem cell (MSC) transplantation, as a potential strategy for regulating neuroinflammation, has received extensive attentio...