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Empasiprubart (ARGX-117) is a humanized recycling antibody that prevents binding of C2 to C4b, blocking downstream classical and lectin pathways of complement activation. Empasiprubart binds to the CCP2 domain of complem...

Abstract Purpose Structured reporting (SR) offers standardized radiological documentation, enhancing clarity and reproducibility. However, its role in contrast-enhanced ultrasound (CEUS) for testicular tumors remains und...

ObjectiveThis study aimed to explore the influencing factors and structural changes in hospitalization expenses for heart failure (HF) patients under the Diagnosis-Related Group (DRG) payment system reform, providing a s...

Despite the widely use and multiple validations of the EURO-D scale, its factor structure is still under debate. Exploratory Graph Analysis (EGA), a novel network psychometric method, offers a promising approach to exami...

Abstract Background Organizing free-text patient data into a structured format is labor-intensive and time-consuming. This study aims to evaluate the effectiveness of a fine-tuned lightweight language model in structurin...

This study examines the impact of demand uncertainty on the capital structure of South Korean small and medium-sized enterprises (SMEs) from 2000 to 2019. Unlike the previous studies, utilizing a two-stage approach, the ...

Abstract We developed SPARFlow, an open-source KNIME workflow for structure–activity or structure–property relationship (SAR/SPR) analyses. The workflow integrates data preprocessing, chemical structure curation, sim...

Against the background of global climate change, increasingly severe drought stress exerts a significant impact on plant growth and yield. This study aimed to clarify the leaf anatomical structure, physiology and biochem...

In order to study the microscopic damage characteristics of marble by explosive impact loading, we carried out the blasting test of marble with different charges, analyzed the microcrystalline structure of marble specime...

BackgroundMango (Mangifera indica L.) is an economically important tropical fruit crop, yet the genomic diversity of mango germplasm from the Jazan region of Saudi Arabia—the country's primary production hub—remains ...

Background. The increase in technogenic electromagnetic load leaves open the question of its impact on living cells, which do not have a specific evolutionary mechanism for responding to such an environmental factor. Cur...

Abstract Background Modern medical education is transforming from a biomedical focus toward a holistic, patient-centered paradigm that values medical humanistic qualities, such as empathy, communication skills and reflec...

Abstract This study investigates the effect of board structure on accrual and real earnings management in Ethiopia. Before the enactment of Proclamation No. 1248/2021 and the subsequent official market launch in 2025, Et...

Abstract This study aimed to explore the associations among personality traits, gender roles, and team cohesion in youth athletes using network analysis and regression modeling. A sample of 518 youth athletes aged 12–1...

Abstract Background Non-suicidal self-injury (NSSI) poses a serious threat to adolescents’ physical and mental health. This study aims to systematically examine the network structure of the relationship between adolesc...

Electric vehicles (EVs) have experienced rapid growth in emerging markets; however, aggregate expansion does not necessarily reflect stable adoption intention. This study examines a “perception–intention gap” in Th...

Abstract Recent advances in protein structure prediction have opened new avenues for understanding the potential impact of genetic mutations and how they might affect protein structure. In this study, we analyzed the dis...

This study prepared a series of NH2-MIL-125(Ti) samples (denoted as NMT-x%) by tuning the methanol fraction (20%, 30%, 40%, and 50%) in a mixed methanol/N,N-dimethylformamide (MeOH/DMF) solvent system, and investigated t...

Abstract A heated debate has been ongoing regarding the potential overlap in language disorders exhibited by children with developmental language disorder (DLD) and those with autism spectrum disorder plus language impai...

IntroductionExcessive plantar pressure has been recognized as a key risk factor for diabetic foot ulceration.MethodsTo address this problem, a partition-infilled functional insole based on triply periodic minimal surface...

Abstract Background Traumatic brain injury (TBI) needs inter-disciplinary care through pre-hospital resuscitation, emergency and neurosurgical care, neurocritical care, and structured neurorehabilitation to maximize surv...

ABSTRACT Jackfruit (Artocarpus heterophyllus) thrives in subtropical and tropical areas but is vulnerable to winter cold stress. The myeloblastosis (MYB) transcription factor family plays an important role in plant biolo...

Background Residents in difficulty represent a significant challenge in postgraduate medical education. Early, structured remediation may improve academic and clinical performance, yet regional evidence from family medic...

Coastal areas are dynamic environments shaped by the interaction between natural processes and human activities. Rapid urbanization and land use transformations increasingly threaten the ecological integrity and spatial ...