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Impact of small area-level deprivation on survival outcomes in patients with Cholangiocarcinoma: a population-based multilevel survival analysis
Artículo
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Impact of small area-level deprivation on survival outcomes in patients with Cholangiocarcinoma: a population-based multilevel survival analysis
Jonghyun Lee et al · Frontiers Media S.A · 2026 · ISSN 2296-2565
BackgroundCholangiocarcinoma (CCA) carries a dismal prognosis. Beyond clinical determinants, socioeconomic deprivation may also influence outcomes. Busan, a rapidly aging metropolitan area in Korea, provides a critical s...
LCC LCC:Public aspects of medicineIdioma eng
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Association of heart rate recovery with mortality risk in a 72-month survival analysis
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Association of heart rate recovery with mortality risk in a 72-month survival analysis
Bruno Margueritte Costa et al · Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz · 2026 · ISSN 1678-4464
This study aimed to investigate whether heart rate recovery (HRR) is a predictor of all-cause mortality in a 72-month survival analysis. In this cohort study, 578 individuals who underwent a maximal exercise test at a un...
LCC LCC:Medicine; LCC:Public aspects of medicineIdioma eng
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Survival benefits of immunotherapy combined with chemoradiotherapy in metastatic colorectal cancer: an analysis based on data from the SEER database
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Survival benefits of immunotherapy combined with chemoradiotherapy in metastatic colorectal cancer: an analysis based on data from the SEER database
Zhang Jie et al · De Gruyter · 2026 · ISSN 2391-5463
Chemoradiotherapy (CRT) alone shows limited efficacy in improving outcomes for metastatic colorectal cancer (mCRC) patients. This study aimed to comprehensively evaluate the survival benefits of combining CRT with immuno...
LCC LCC:MedicineIdioma eng
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Survival and predictors of mortality among adults with type 2 diabetes at a teaching hospital in Ghana: a retrospective cohort study
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Survival and predictors of mortality among adults with type 2 diabetes at a teaching hospital in Ghana: a retrospective cohort study
Issah Haruna et al · BMC · 2026 · ISSN 1471-2458
Abstract Background Mortality rates remain high among individuals with type 2 diabetes. The rising cases of Diabetes Mellitus (DM) have negatively impacted society’s development, health and have impoverished individual...
LCC LCC:Public aspects of medicineIdioma eng
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Conditional survival rates after neoadjuvant chemoradiotherapy combined with surgery in intermediate-low locally advanced rectal cancer based on two-centre retrospective analysis
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Conditional survival rates after neoadjuvant chemoradiotherapy combined with surgery in intermediate-low locally advanced rectal cancer based on two-centre retrospective analysis
Guancong Wang et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract To evaluate the temporal changes in 5-year conditional survival (CS5) among patients with intermediate-low locally advanced rectal cancer (LARC) treated with neoadjuvant chemoradiotherapy (nCRT) and surgery, and...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Association between treatment decisions and survival outcomes in lung cancer patients under a multidisciplinary team model: the impact of MDT-recommended treatment plans on treatment completion rates, survival time, and treatment conversion
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Association between treatment decisions and survival outcomes in lung cancer patients under a multidisciplinary team model: the impact of MDT-recommended treatment plans on treatment completion rates, survival time, and treatment conversion
Qian Yi et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
BackgroundThe complexity of lung cancer management requires coordinated care. This study aimed to evaluate the impact of Multidisciplinary Team (MDT)-recommended treatment plans on the treatment course and survival outco...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Efficacy and safety analysis of CAR-T cell salvage therapy in relapsed/refractory diffuse large B-cell lymphoma after failure of bispecific antibody treatment
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Efficacy and safety analysis of CAR-T cell salvage therapy in relapsed/refractory diffuse large B-cell lymphoma after failure of bispecific antibody treatment
Fuli Li et al · BMC · 2026 · ISSN 1479-5876
Abstract Background Patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) who failed bispecific antibody (BsAb) therapy face an extremely poor prognosis, necessitating exploration of effective salva...
LCC LCC:MedicineIdioma eng
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Patterns, survival, and mortality predictors in children with down syndrome and congenital heart disease in resource-limited settings: a follow-up study
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Patterns, survival, and mortality predictors in children with down syndrome and congenital heart disease in resource-limited settings: a follow-up study
Mohammed Nasir et al · BMC · 2026 · ISSN 1471-2431
Abstract Background Down syndrome (DS) is the most common chromosomal disorder associated with congenital heart disease (CHD). However, data on CHD patterns, survival, and mortality predictors among individuals with DS i...
LCC TENDOlBlZGlhdHJpY3M~Idioma eng
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Adherence to endocrine therapy and survival outcomes in hormone receptor–positive breast cancer
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Adherence to endocrine therapy and survival outcomes in hormone receptor–positive breast cancer
Xiao Ju et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
ObjectiveTo evaluate the association between adherence to adjuvant endocrine therapy and overall survival as well as breast cancer–specific survival in patients with hormone receptor–positive breast cancer, to charac...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Impact of germline genetic variation on breast cancer prognosis: a systematic review and meta-analysis
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Impact of germline genetic variation on breast cancer prognosis: a systematic review and meta-analysis
Ariadna Gutiérrez-González et al · BMC · 2026 · ISSN 1471-2407
Abstract Background Breast cancer prognosis is the result of complex interactions between tumor biology, treatment, and host factors. While germline genetic variation is increasingly incorporated into breast cancer risk ...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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A nomogram for predicting the disease-free survival of patients with pancreatic ductal adenocarcinoma
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A nomogram for predicting the disease-free survival of patients with pancreatic ductal adenocarcinoma
Yao Pan et al · BMC · 2026 · ISSN 1471-2342
Abstract Background Accurate prediction of disease-free survival after radical resection in patients with pancreatic ductal adenocarcinoma (PDAC) remains challenging. Therefore, this study establishes and validates a pre...
LCC TENDOk1lZGljYWwgdGVjaG5vbG9neQ~~Idioma eng
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ATG16L1 and OPTN as a novel prognostic gene expression signature in acute myeloid leukemia survival
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ATG16L1 and OPTN as a novel prognostic gene expression signature in acute myeloid leukemia survival
Alexandra Teixeira et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
Acute myeloid leukemia (AML) is the most frequent type of leukaemia in adults, often with poor outcomes due to the complex genetic landscape and low treatment efficacy. Autophagy, a conserved degradation process, plays a...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Business as usual in Transnistria: survival strategies of entrepreneurs in a de facto state
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Business as usual in Transnistria: survival strategies of entrepreneurs in a de facto state
Magdalena Dembińska · Kulturní studia · 2026 · ISSN 2336-2766
This article analyses how small entrepreneurs navigate the political economy of Transnistria, a de facto state characterised by external dependence, oligarchic concentration of power, and geopolitical uncertainty. Drawin...
LCC TENDOkV0aG5vbG9neS4gU29jaWFsIGFuZCBjdWx0dXJhbCBhbnRocm9wb2xvZ3k~Idioma ces
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Cost-effectiveness analysis of neoadjuvant docetaxel plus androgen deprivation therapy before radical prostatectomy in high-risk localized prostate cancer
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Cost-effectiveness analysis of neoadjuvant docetaxel plus androgen deprivation therapy before radical prostatectomy in high-risk localized prostate cancer
Qi Liu et al · Frontiers Media S.A · 2026 · ISSN 2296-2565
ObjectiveHigh-risk localized prostate cancer is often associated with a higher risk of disease progression post-surgery. While radical prostatectomy (RP) is a cornerstone treatment, neoadjuvant chemohormonal therapy (CHT...
LCC LCC:Public aspects of medicineIdioma eng
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Efficacy and prognostic factors of stereotactic radiosurgery versus whole-brain radiotherapy for brain metastases in small cell lung cancer: a systematic review and meta-analysis
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Efficacy and prognostic factors of stereotactic radiosurgery versus whole-brain radiotherapy for brain metastases in small cell lung cancer: a systematic review and meta-analysis
Jun Li et al · BMC · 2026 · ISSN 1471-2407
Abstract Objective To systematically evaluate the efficacy differences between stereotactic radiosurgery (SRS) and whole-brain radiotherapy (WBRT) in treating brain metastases from small cell lung cancer (SCLC), and to a...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Implant survival and factors associated with failure of cemented custom-made distal femoral megaprostheses after tumor resection
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Implant survival and factors associated with failure of cemented custom-made distal femoral megaprostheses after tumor resection
Apostolopoulos Vasileios et al · EDP Sciences · 2026 · ISSN 2426-8887
Background: Distal femoral megaprosthetic reconstruction is a standard limb-salvage procedure after tumor resection. This study aimed to evaluate implant survival and associated factors, the incidence of mechanical failu...
LCC TENDOk9ydGhvcGVkaWMgc3VyZ2VyeQ~~Idioma eng
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Is PD-1/PD-L1 inhibitor plus bevacizumab superior to sorafenib as first-line treatment for advanced hepatocellular carcinoma? A pooled analysis of four phase 3 RCTs
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Is PD-1/PD-L1 inhibitor plus bevacizumab superior to sorafenib as first-line treatment for advanced hepatocellular carcinoma? A pooled analysis of four phase 3 RCTs
Qisheng Zhong et al · BMC · 2026 · ISSN 1471-230X
Abstract Background Sorafenib has served as standard treatment for advanced hepatocellular carcinoma (HCC). Recently, several randomized controlled trials (RCTs) have explored the use of programmed cell death protein 1/p...
LCC LCC:Diseases of the digestive system. GastroenterologyIdioma eng
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Prediction models in prostate cancer: a systematic review and meta-analysis
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Prediction models in prostate cancer: a systematic review and meta-analysis
Emmanuel Nsedu Israel et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
BackgroundProstate cancer is the sixth most common cause of cancer-related death in males globally and is often identified as a secondary malignancy. Early detection and appropriate management increase the patient’s li...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Prognostic factors and survival outcomes in patients undergoing limb-sparing surgery for primary malignant bone tumors
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Prognostic factors and survival outcomes in patients undergoing limb-sparing surgery for primary malignant bone tumors
Chunan Zhong et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
BackgroundPrimary malignant bone tumors are aggressive neoplasms that frequently affect adolescents and young adults. Limb-sparing surgery (LSS) has become the preferred surgical approach when oncologically feasible; how...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Prognostic implications of PD-L1 expression in gastric cancer: systematic review and meta-analysis of studies published between 2018 and 2025
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Prognostic implications of PD-L1 expression in gastric cancer: systematic review and meta-analysis of studies published between 2018 and 2025
Gulnaz Yessultanova et al · BMC · 2026 · ISSN 1471-2407
Abstract Background Programmed death-ligand 1 (PD-L1) is widely used as a predictive biomarker for response to immune checkpoint inhibitors in gastric cancer (GC); however, its independent prognostic value for overall su...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Prognostic model for predicting recurrence-free survival in HBV-related hepatocellular carcinoma patients after combined treatment: a multicenter study
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Prognostic model for predicting recurrence-free survival in HBV-related hepatocellular carcinoma patients after combined treatment: a multicenter study
Bojun Liu et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
IntroductionHepatocellular carcinoma (HCC) is a lethal malignancy, with hepatitis B virus (HBV) infection as its leading cause in China. Transarterial chemoembolization (TACE) combined with radiofrequency ablation (RFA) ...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Upstaging Risk and Prognosis of Clinical T2-3N0M0 Esophageal Squamous Cell Carcinoma Patients after a Curative Esophagectomy: A Propensity Score-Matched Analysis
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Upstaging Risk and Prognosis of Clinical T2-3N0M0 Esophageal Squamous Cell Carcinoma Patients after a Curative Esophagectomy: A Propensity Score-Matched Analysis
Ping-Chung Tsai et al · Korean Society for Thoracic & Cardiovascular Surgery · 2026 · ISSN 2765-1606
Background: Neoadjuvant chemoradiation therapy (nCRT) has survival benefits for patients with cT1N1 or cT2–3N0-1 esophageal squamous cell carcinoma (ESCC), but heterogeneous disease behavior has been observed in node...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Outcome analysis and associations with Charlson comorbidity index in the early-stage lung cancer patients treated with stereotactic radiotherapy
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Outcome analysis and associations with Charlson comorbidity index in the early-stage lung cancer patients treated with stereotactic radiotherapy
Dasantha Jayamanne et al · BMC · 2026 · ISSN 1471-2407
Abstract Background Lung stereotactic body radiotherapy (SBRT) is the standard of care for patients with inoperable early-stage non-small cell lung cancer (NSCLC), who frequently have significant comorbidities. There is ...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Comprehensive clinicopathological and prognostic analysis of primary pulmonary lymphoepithelial carcinoma: a retrospective cohort study
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Comprehensive clinicopathological and prognostic analysis of primary pulmonary lymphoepithelial carcinoma: a retrospective cohort study
Meihong Yao et al · BMC · 2026 · ISSN 1746-1596
Abstract Background Primary pulmonary lymphoepithelial carcinoma (PPLEC) is an extremely rare subtype of lung squamous cell carcinoma (LUSC). This study aims to comprehensively characterize clinicopathological and molecu...
LCC TENDOlBhdGhvbG9neQ~~Idioma eng
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