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ObjectiveObstructive sleep apnea (OSA) is increasingly recognized for its association with significant morbidity and mortality. Despite advances in understanding OSA’s impacts, the role of systemic inflammation in this...

Abstract Purpose Magnesium plays a role in various physiological processes and has been used for treatment and prevention of diseases affecting different organ systems. Magnesium sulfate has been proposed as an adjuvant ...

BackgroundUlceration is a common complication of infantile hemangioma, and its management poses unique difficulties when the lesion is located in high-risk areas like the scrotum. This case report details the successful ...

Harnessing root-associated microbiomes to promote beneficial microbial compositions could offer a sustainable strategy to increase crop resilience. Major challenges impeding this strategy are the lack of understanding of...

Huangtao Ruan,1,2,* Xiaozhao Lu,2,3,* Huan Lu,2– 4,* Haozhang Huang,2,3,* Zuxian Huang,1,2 Shangyi Tang,2,3 Ziyao Yuan,2,5 Rengui Jiang,2,3,6 Jiazhen Xin,6 Tao Tang,6 Jin Liu,1,2 Yong Li...

Abstract Objective To investigate the association between the Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and in-stent restenosis (ISR) following percutaneous coronary intervent...

BackgroundThe systemic immune-inflammation index (SII) has emerged as a widely studied inflammatory biomarker reflecting the balance between host inflammatory and immune status, although evidence in lung cancer patients ...

ObjectiveSystemic inflammatory response plays a key role in the pathogenesis of endometriosis. This study aimed to investigate the association between the aggregate index of systemic inflammation (AISI), defined as neutr...

ObjectiveSarcopenia is a progressive and complex disorder associated with higher morbidity and mortality, which significantly increases the financial burden and medical costs. This study aims to investigate the relations...

Abstract Background Pulmonary hypertension (PH) is a serious and potentially life-threatening complication of systemic lupus erythematosus (SLE). Functional characterization may facilitate the differentiation of the hete...

Abstract Lupus retinopathy (LR) is one of the most frequent and serious ocular complications of systemic lupus erythematosus (SLE), because it may cause irreversible visual impairment. The aim of this study was to evalua...

ABSTRACT Introduction Systematic lupus erythematosus is a complex fundamental autoimmune disease with relapsing‐remitting course and spectrum of disease ranging from mild to life‐threatening illness. Approximately ha...

Abstract Background This study was motivated by the high prevalence of anemia of inflammation (AI) in systemic lupus erythematosus (SLE) and the poorly explored potential link between the underlying inflammatory drive an...

Danyang Yang,1 Xin Liu,1 Wenwen Jing,1 Xu Feng,1 Canying Lai,1 Chenyue Liu,2 Zhigang Xu,1,3 Yangang Zhang,1 Jiayi Han,1 Songmei Geng,1 Ruilian Li,1 Dan Li,4 Boyi Cheng,1 Yufei Wu,1 Zhuokun Liu,1 Jialin Lian,1 Zhenghui Wa...

Abstract Background Pediatric sepsis remains a leading cause of global mortality, necessitating early and accurate risk stratification. Traditional scoring systems often fail to capture the rapid, non-linear progression ...

ABSTRACT The cGAS‐STING pathway is emerging as an essential driver in systemic lupus erythematosus (SLE). Here, we characterize the key signature of cGAS‐STING pathway and its roles in SLE by leveraging large‐scale...

BackgroundRecessive dystrophic epidermolysis bullosa (RDEB) is a devastating genodermatosis caused by biallelic COL7A1 mutations, where chronic inflammation drives disabling complications affecting quality of life and su...

BackgroundThe prevalence of female sexual dysfunction (FSD) among women with systemic lupus erythematosus (SLE) is inconsistent, and whether SLE is a risk factor for FSD among women remains controversial. Therefore, this...

Background: Screening instruments are brief and simple tools designed to identify alterations in cognitive functioning, as well as to rule out or confirm the presence of cognitive dysfunction. Systemic lupus erythematosu...

Malignant hypertension is a medical emergency characterized by severe elevation in blood pressure with end-organ damage, including ocular involvement. Systemic lupus erythematosus (SLE) may result from lupus nephritis or...

BackgroundTransarterial chemoembolization (TACE) is a standard treatment for intermediate-stage hepatocellular carcinoma (HCC), but its efficacy varies due to patient heterogeneity. Combining TACE with systemic therapies...

Abstract Unmanned Aerial Vehicle (UAV) operations confront complex systemic risks that challenge traditional analytical methods. This paper develops a hierarchical Bayesian Network (BN) to quantitatively model these risk...

Early adversity programs induce changes that can accelerate biological aging. Using the early stress model of maternal separation (MS), we assessed oxidative, metabolic, and biochemical consequences in serum derived from...

ABSTRACT Background and Objectives Systemic inflammation indices derived from complete blood counts (CBC) are accessible markers of inflammatory burden, but their relationship with circulating cytokines in psoriasis rema...