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C1q deficiency is an inheritable immune disorder attributed to biallelic pathogenic mutations in C1q genes (C1QA, C1QB, or C1QC). Patients with C1q deficiency demonstrate increased susceptibility to severe infections and...

Thrombotic thrombocytopenic purpura (TTP) is a rare, life threatened disease. It is characterized by fever, variable neurological manifestations, progressive renal failure, microangiopathic hemolytic anemia and thrombocy...

Objective: The aim of the study was to analyze the indications, efficacy, and complications of therapeutic plasma exchange (plasmapheresis) applied for renal diseases in three years retrospectively. Materials and Metho...

OBJECTIVE: Therapeutic plasma exchange (TPE) has been used in many diseases as primary or adjunctive therapy. We present our TPE experience in a pediatric nephrology practice setting. MATERIAL and METHODS: We retrospe...

ABSTRACT Background and Aims Despite growing interest in the role of vitamin D in various infectious diseases, limited evidence exists regarding its association with platelet (PLT) parameters in patients with COVID‐19 ...

Atypical hemolytic uremic syndrome (aHUS) is a disorder characterized by a propensity to thrombotic microangiopathy (TMA) due to defective regulation of the alternative complement pathway. Mutations in genes encoding com...

INTRODUCTION: To determine the symptoms, clinical characteristics, prevalence and outcome of patients with hypernatremia who presented at the emergency department. MATERIAL and METHODS: We retrospectively studied patie...

Metabolic syndrome (MetS) is a cluster of metabolic disturbances increasing a risk of cardiovascular diseases and diabetes 2 types. The main features of MetS include atherogenic dyslipidemia, elevated blood pressure, ins...

In clinical practice, plasmapheresis is utilized to remove circulating immune complexes, endotoxins and high molecular weight molecules such as lipoproteins containing cholesterol. It is useful in certain diseases in rhe...

The antiphospholipid antibody syndrome (APS) is characterized by antibodies directed either at plasma proteins bound to phospholipids or at the phospholipids themselves. APS is referred to as primary when it occurs alone...

Abstract Objectives To evaluate the prevalence, associated factors, and prognostic performance of NIH activity index–defined interstitial inflammation (NIH-TII) and interstitial fibrosis and tubular atrophy (IFTA) in l...

All intravenous immunoglobulin (IVIG) products carry a boxed warning for the risks of renal dysfunction and thromboembolic events (TEEs). Patient-related thrombotic risk factors include hyperviscosity, a condition in whi...

Materias / palabras clave: vascular biology, thrombotic diseases, hemorrhagic diseases, blood coagulation disorders, fibrinolysis; Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system