Buscar recursos académicos

Abstract Purpose This study aims to investigate the mechanisms underlying ANXA1 and HMGB1-regulated autophagy in relation to growth and radioresistance in thyroid cancer cells. This exploration seeks to provide new theor...

BackgroundPatients with differentiated thyroid cancer (DTC) undergoing radioactive iodine (RAI) therapy experience concurrent physical and psychological symptoms, yet the dynamic interplay among these symptoms remains in...

Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer, and its incidence has been increasing recently. Although the 5-year survival rate for PTC remains stable, the prognosis for medullary thyroid c...

Abstract Although papillary thyroid cancer (PTC) genetic research has advanced from identifying driver genes to investigating susceptibility loci and gene-environment interactions, data in Chinese populations remain limi...

Background: Thyroid cancer is one of the most prevalent endocrine neoplasms in Brazil, and radioiodine therapy (RAI) is a well-established adjuvant treatment. However, managing RAI can be particularly challenging in pati...

Abstract Background The spine is an uncommon metastatic location from thyroid cancer. Here, we describe our experience with spinal cord compression as presentation of metastatic thyroid carcinoma, including surgical mana...

Hypereosinophilic syndrome (HES) is characterized by blood or tissue hypereosinophilia leading to organ damage or dysfunction. HES is most commonly secondary or idiopathic, but may be primary (myeloid) or familial. Here,...

Background: Cuproptosis, a copper-dependent form of programmed cell death, has been implicated in the progression of various cancers. However, the role of LOXL2 - a cuproptosis-related gene (CRG) - and its prognostic val...

PurposeThis study aimed to describe the clinicopathological landscape of thyroid disease, summarize long-term management trends of thyroid carcinoma (TC) and lymph node metastasis (LNM) from 1999 to 2018, and develop a n...

Abstract Papillary Thyroid Cancer (PTC) is one of the most prevalent endocrine malignancies, and its incidence rate has almost tripled over the past three decades. The current study aimed to identify gene alterations and...

Abstract Background Circulating cell-free DNA (cfDNA) is a promising biomarker for non-invasive early cancer detection. We integrated methylation entropy, a measure of DNA methylation heterogeneity, with other cfDNA feat...

ABSTRACT Background Cancer is a significant global health challenge, affecting millions of people every year. Overall survival rates have improved over time, but some patients exhibit treatment resistance, prompting ongo...

Rongzhi Huang,1,* Zexu Zhan,1,* Shulin Huang,1 Wenlong Cao,1 Jiehua Li,1 Min Mao2 1Department of Gastrointestinal and Gland Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, T...

Xue Yu,1,* Min Wu,2,* Lei Liu,3 Chun Zhang1 1Department of Breast Surgery, Peking University International Hospital, Beijing, People’s Republic of China; 2Department of Breast & Thyroid Surgery, Bei...

While most thyroid cancers have a favorable prognosis, anaplastic thyroid carcinoma (ATC) is highly aggressive and results in a poor prognosis. ATC frequently arises from preexisting benign goiters or highly differentiat...

Antithyroglobulin antibodies (TgAb) are present in 10–25% of patients with differentiated thyroid cancer (DTC) and significantly affect the reliability of serum thyroglobulin (Tg) measurements during follow-up. Beyond ...

Abstract Cuproptosis is a recently identified copper-dependent cell death pathway with growing relevance in tumor biology, yet its involvement in thyroid carcinoma (TC) remains poorly understood. In this study, we integr...

Weiya Zhuang,1 Daozhe Lin,2 Chengliang Chen2 1Department of Gynecology and Obstetrics, The Third Affiliated Hospital of Wenzhou Medical University, Ruian, Zhejiang, People’s Republic of China; 2Department of Thyroid an...