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The effects of replacing Tifton hay with castor bean hulls (0, 33, 66 and 100%) on the leg tissue composition, chemical composition, physicochemical parameters and sensorial traits of sheep meat were studied. A total of ...

The Drosophila I-Smad Dad uses MH1-mediated transcriptional regulation in wing tissue but both MH1- and MH2-mediated mechanisms in neurons. Inhibitory Smads (I-Smads) regulate TGF-β/BMP signaling through multiple distin...

The loss or failure of an organ or tissue is one of the most frequent, devastating, and costly problems in human health care. A new field, tissue engineering, applies the principles of biology and engineering to the deve...

Thrombolytic therapy for acute ischemic stroke has been approached cautiously because there were high rates of intracerebral hemorrhage in early clinical trials. We performed a randomized, double-blind trial of intraveno...

The aim of the study was to characterize the preclinical pharmacokinetics and comparative pharmacokinetics of pure vitexin-2"-O-rhamnoside (VR) in mice after oral and intravenous administration at dose of 30 mg/kg. A sen...

Resolving the molecular details of proteome variation in the different tissues and organs of the human body will greatly increase our knowledge of human biology and disease. Here, we present a map of the human tissue pro...

Abstract Background Optimization of biotechnological processes is traditionally limited by time-consuming trial-and-error approaches and the complexity of simultaneously optimizing multiple, often conflicting objectives....

IntroductionIndividuals with obesity may be at a higher risk of developing severe periodontitis. We previously reported that C-C motif ligand 19 (CCL19) plays a pivotal role in adipose inflammation in obesity and that ad...

ABSTRACT Spinal cord injury (SCI), which is a severe complication of spinal fractures, often causes the dysfunction of the spinal cord and results in sensory and motor abnormalities. Current clinical treatments—includi...

Background: BPC-157 and GHK-Cu are synthetic peptides with potential in tissue repair, influencing molecular mechanisms in healing, angiogenesis and inflammation. Objective: This review synthesizes preclinical and cli...

The increasing prevalence of artificial light sources has rendered blue light (BL) a novel environmental metabolic disruptor. This study aimed to investigate the potential effects of BL exposure on mitochondrial function...

Abstract We hypothesized that supplementing finishing diets with palm oil would promote adipogenic gene expression but depress stearoyl-CoA desaturase (SCD) gene expression in intramuscular (i.m.) adipose tissues of Hanw...

Abstract A novel method was proposed to design the structure of a bone tissue engineering scaffold based on triply periodic minimal surface. In this method, reverse engineering software was used to reconstruct the surfac...

The Developmental Origins of Health and Disease theory describes early life as a critical window for long-term metabolic health. Accumulating evidence has identified the gut microbiota as a key mediator of early-life met...

Vertical root fractures of intentional replantation need a material capable of binding the fragments of the fracture line tightly and encouraging the regeneration of periradicular tissue. One of the indicators that regen...

Abstract Background Increased gene transcription of hypoxia‐induced mediators of fibrosis in renal tissue has been identified in experimentally induced, ischemic chronic kidney disease (CKD). Objective To characterize ...

Soluble carbohydrates distribution depends on plant physiology and, among other important factors, determines fruit yield and quality. In plant biology, the analysis of sugars is useful for many purposes, including metab...

Thyroid hormones play a key role in adipose tissue development and function. Hypothyroidism (HypoT) can delay mammary tumor development in rats, possibly by altering mammary adipose tissue (MAT) and its interaction with ...

Introduction and aims: Healing abutment dislodgement is a common clinical complication in dental implantology, yet its impact on peri-implant soft tissue immunity remains unclear. This exploratory pilot study aimed to in...

ABSTRACT There is a growing interest in the study of unspecialized mesenchymal stem cells, for there are still some discussions about their in vitro behavior. Regenerative medicine is a science undergoing improvement whi...

Central obesity is characterized by visceral adipose tissue (VAT) expansion, considered one of the main risk factors for metabolic complications. In recent years, new drugs have been studied for obesity treatment. Liragl...

A growing number of studies are now utilizing human organotypic brain slice cultures (OBSC), enabled by improved long-term culture protocols that support the investigation of human-specific cellular physiology. Human OBS...

Abstract Objective Tissue-resident memory T (TRM) cells play a key role as “immune sentinels” in mucosal immune protection. However, the molecular regulatory mechanisms underlying the formation and long-term resid...

In the present study, oxidative system status both in plasma and renal tissue of rats with adriamycin induced experimental rat nephrotic syndrome was investigated. Glutathion peroxidase (GSH-Px) activities and malondiald...