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The aim of this study was to establish the action of 1% tetracaine eye drops in combination with 0.1% phenylephrine in two different posologies and their effects on the eye compared to the 0.5% proparacaine drops in dogs...

The objective of the present investigation was to develop and evaluate microemulsion-based hydrogel (MBH) for the topical delivery of sinomenium. The solubility of sinomenium in oils and surfactants was evaluated to iden...

Nanoemulsions are special emulsions that consist in a very small drop with sizes between 20 to 500 nm. When they are intended for topical application, the main problem of nanoemulsions is their low viscosity, which is re...

Non-irritant, non-comedogenic and non-polar emollients were pre-selected for determinations of relative dielectric permittivity and solubility of benzoyl peroxide (BP). Those solvents capable of solubilizing BP in concen...

Acne vulgaris is a common disease of adolescence that occurs in approximately80% of the population aged 11-30 years. The disease greatlyreduces well-being and self-esteem. In the pathogenesis of acne vulgarismany factors...

Aim of the study: In this study the anti-inflammatory activity of aqueous, dichloromethane (CH2Cl2) and methanolic (MeOH) extracts and two major compounds isolated from Lithrea molleoides (Vell.) Engl. (Anacardiaceae) we...

‘To mention Europe’s Christian roots implies indicating as well the residual sources of moral orientation, which is a factor of Europe's identity.’ [Joseph Ratzinger, Europe’s Crisis of Culture] This study will a...

Introduction. Herpes zoster oticus is caused by varicella zoster virus(VZV), affecting 10-20% of the population. Ramsay Hunt syndrome,a complication of herpes zoster oticus, presents a reactivation of latentVZV infection...

Hydroquinone (HQ) is a drug reported to possess manifold biological activities. HQ is highly unstable into various topical vehicles, presenting low topical bioavailability and a relevant level of toxicity. The Pluronic®...

Studies to evaluate the clinical efficacy and safety of various topical NSAIDS compared to oral NSAIDS have been reported but little research has been conducted to evaluate the efficacy of topical NSAIDS from different m...

Inhibition action of propylene glycol (PG) on the antifungal activity of fluconazole has been investigated. PG was used as cosolvent and penetration enhancer in different solutions and topical dosage forms. The interacti...

The deposition of chlorhexidine base on thermosensitive N-isopropylacrylamide polymeric microparticles was assessed in this study using energy dispersive X-ray spectrometry (EDXS) in scanning electron microscopy (SEM) se...