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Abstract Prostate cancer (PCa) is a leading malignancy in men, particularly challenging in its advanced stages due to treatment resistance and immune evasion. MicroRNA-1290 (miR-1290) was identified to be implicated in t...

IntroductionLung cancer remains the leading cause of cancer-related mortality worldwide. Drug resistance is a major limitation of current therapies, prompting the search for new treatment strategies. Lung tumors frequent...

Bone metastasis is a frequent and incurable consequence of advanced prostate cancer (PC). This process originates through an interplay between disseminated tumor cells and heterogeneous bone resident cells in the metasta...

Medicarpin (MED) is an isoflavonoid compound derived from traditional Chinese medicine (TCM). Numerous preliminary experimental studies have shown that MED has significant pharmacological effects in the treatment of canc...

Persistent cervical human papillomavirus (HPV) infection is the key biological event underlying high-grade squamous intraepithelial lesions, cervical cancer development, and recurrence risk. Botanical drugs and their bio...

Chemotherapy-induced gastrointestinal dysfunction (CIGD) is a multifactorial clinical syndrome that substantially limits treatment tolerance, continuity, and quality of life in patients with cancer. Although targeted the...

Materias / palabras clave: translational cancer therapeutics, precision oncology and biomarker development, molecularly guided clinical trials, mechanisms of therapeutic response and resistance, experimental and early-phase oncology, bench-to-beds...

Materias / palabras clave: clinical studies, translational therapeutics, molecular diagnostics, genetics and genomics, cellular and molecular biology, epidemiology; Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and car...

Materias / palabras clave: molecular mechanisms of cancer, cancer genomics and tumor evolution, functional and systems oncology, biomarker discovery and validation, translational and experimental therapeutics, precision oncology research; Medicine...