NODOVOX | Discovery

Journal of Trial and Error

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Journal of Trial and Error

JOTE Publishers · ISSN 2667-1204

Materias / palabras clave: Social Sciences: Social sciences (General)

Idioma English

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Journal of Trial and Error

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Journal of Trial and Error

JOTE Publishers; Netherlands · ISSN 2667-1204

Materias / palabras clave: metascience, trial and error, publication ethics, failure, multidisciplinary research; Social Sciences: Social sciences (General)

Idioma English

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Comparative evaluation of Bayesian external information borrowing and frequentist approaches in underpowered confirmatory trials

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Comparative evaluation of Bayesian external information borrowing and frequentist approaches in underpowered confirmatory trials

Ruobing Li et al · BMC · 2026 · ISSN 1471-2288

Abstract The application of Bayesian statistics in pivotal clinical trials has gained increasing attention, particularly for underpowered confirmatory trials such as those in pediatric and rare disease populations. Bayes...

LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng

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Impact and Perspectives of Registry-Based Research in Inborn Errors of Immunity/Primary Immune Disorders: Insights from the ESID Registry of 36,681 Patients

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Impact and Perspectives of Registry-Based Research in Inborn Errors of Immunity/Primary Immune Disorders: Insights from the ESID Registry of 36,681 Patients

Markus G. Seidel · Rockefeller University Press · 2026 · ISSN 3065-8993

Clinical research and real-world observational studies are essential for advancing the diagnosis and treatment of rare diseases, such as inborn errors of immunity/primary immune disorders (IEI/PID). To support efficient ...

LCC LCC:Immunologic diseases. AllergyIdioma eng

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Prospective Clinical Trial of Mycophenolate Mofetil (MMF) Duration De-Escalation in Allogeneic Hematopoietic Cell Transplantation (HCT) for Inborn Errors of Immunity: Is MMF Dispensable After Reduced Intensity Conditioning, Posttransplantation Cyclophosphamide(Ptcy)-Based HCT?

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Dimana Dimitrova et al · Rockefeller University Press · 2026 · ISSN 3065-8993

Hematopoietic cell transplantation (HCT) offers curative potential for inborn errors of immunity (IEI) patients, who often enter HCT with significant comorbidities and disease sequelae, active infections, and/or limited ...

LCC LCC:Immunologic diseases. AllergyIdioma eng

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Manufacturing Process Simulation – On Its Way to Industrial Application

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Manufacturing Process Simulation – On Its Way to Industrial Application

Dennis Otten et al · Embry-Riddle Aeronautical University · 2018 · ISSN 2374-6793

Manufacturing process simulation (MPS) has become more and more important for aviation and the automobile industry. A highly competitive market requires the use of high performance metals and composite materials in combi...

LCC LCC:Motor vehicles. Aeronautics. AstronauticsIdioma eng

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Internal standard-assisted ab initio MD simulation for comparative thermal stability and decomposition mechanisms of energetic materials

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Internal standard-assisted ab initio MD simulation for comparative thermal stability and decomposition mechanisms of energetic materials

Ying Xiong et al · KeAi Communications Co. Ltd · 2026 · ISSN 2666-6472

Thermal stability is one of the most important and fundamental properties of energetic molecules, and still suffers from many challenges in theoretical evaluation prior to experiment determination. This work introduces a...

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Modulation of feedback-related negativity by objective and subjective response correctness

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Modulation of feedback-related negativity by objective and subjective response correctness

Yasuhisa Maruyama et al · Nature Portfolio · 2026 · ISSN 2045-2322

Abstract Monitoring actions and outcomes is essential for flexible adaptation to environmental demands. Information about errors is important regardless of whether it is internally generated or externally signaled. Follo...

LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng

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Perceptual–motor performance and neural conduction asymmetries in elite basketball players

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Perceptual–motor performance and neural conduction asymmetries in elite basketball players

Meltem Devrilmez et al · BMC · 2026 · ISSN 2052-1847

Abstract Background This study investigated whether the dominant hand would exhibit faster nerve conduction velocity, lower muscle activation latency, and superior Coincidence Anticipation Timing (CAT) performance compar...

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Quantum Computing and Quantum Technologies in Drug Discovery and Therapeutics: Evidence, Benchmarking, and Translational Integration

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Quantum Computing and Quantum Technologies in Drug Discovery and Therapeutics: Evidence, Benchmarking, and Translational Integration

Niazi SK · Dove Medical Press · 2026 · ISSN 1177-8881

Sarfaraz K Niazi Department of Pharmaceutical Sciences, University of Illinois, Chicago, IL, 60612, USACorrespondence: Sarfaraz K Niazi, Email sniazi3@uic.eduAbstract: Quantum technologies—quantum computing, quantum se...

LCC LCC:Therapeutics. PharmacologyIdioma eng

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Integrated FEA framework for chassis design and failure prediction in SAE supra vehicles

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Integrated FEA framework for chassis design and failure prediction in SAE supra vehicles

Bobby Kurian Samson et al · EDP Sciences · 2026 · ISSN 2100-014X

This paper will offer a unified strategy to the optimization of the chassis of a Formula SAE Supra car and predict structural failures using machine learning and Finite Element Analysis (FEA). The work demonstrates that ...

LCC TENDOlBoeXNpY3M~Idioma eng

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The evolution of projectile points and technical systems: A case from Northern Patagonian coast (Argentina)

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The evolution of projectile points and technical systems: A case from Northern Patagonian coast (Argentina)

Cardillo, Marcelo et al · Elsevier · 2014 · ISSN 2352-409X

In this paper we present the results of the phylogenetic analysis of projectile points dating from the Middle-Late and final Late Holocene recovered from different sites along the coast of San Matías Gulf (Río Negro pr...

Idioma eng

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ADAM: advanced design and AI-driven modeling for plant tissue culture media optimization

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ADAM: advanced design and AI-driven modeling for plant tissue culture media optimization

Hans Bethge et al · BMC · 2026 · ISSN 1746-4811

Abstract Background Optimization of biotechnological processes is traditionally limited by time-consuming trial-and-error approaches and the complexity of simultaneously optimizing multiple, often conflicting objectives....

LCC TENDOlBsYW50IGN1bHR1cmU~; LCC:Biology (General)Idioma eng

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Effects of repetitive peripheral magnetic stimulation on upper extremity motor function recovery after stroke: a meta-analysis and dose-response study

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Effects of repetitive peripheral magnetic stimulation on upper extremity motor function recovery after stroke: a meta-analysis and dose-response study

Liu Hui et al · Frontiers Media S.A · 2026 · ISSN 1664-2295

BackgroundRepetitive peripheral magnetic stimulation (rPMS), a representative non-invasive neuromodulation technique, is widely utilized for the recovery of motor dysfunction following stroke. Although its clinical effic...

LCC LCC:Neurology. Diseases of the nervous systemIdioma eng

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From empirical vaccinology to predictive systems-based vaccine design: multi-omics integration, artificial intelligence, and global equity challenges

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From empirical vaccinology to predictive systems-based vaccine design: multi-omics integration, artificial intelligence, and global equity challenges

Nicole Simone De Lima Coelho et al · Frontiers Media S.A · 2026 · ISSN 2674-0702

Although vaccination remains one of the most impactful interventions in contemporary public health, with consistent and widely documented reductions in morbidity and mortality, the traditional empirical development of va...

LCC TENDOlBoeXNpb2xvZ3k~Idioma eng

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Influence of rhythmic music game intervention on executive function and sensorimotor ability of children with attention deficit hyperactivity disorder

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Influence of rhythmic music game intervention on executive function and sensorimotor ability of children with attention deficit hyperactivity disorder

Honghui Zhu · Frontiers Media S.A · 2026 · ISSN 2296-2565

ObjectiveTo investigate the effectiveness of rhythmic music game–based intervention in improving executive functions and sensorimotor abilities among children with Attention-Deficit/Hyperactivity Disorder (ADHD), there...

LCC LCC:Public aspects of medicineIdioma eng

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Psicologia jurídica e tomada de decisão em situações envolvendo abuso sexual infantil Forensic psychology and decision making in situations involving child sexual abuse

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Psicologia jurídica e tomada de decisão em situações envolvendo abuso sexual infantil Forensic psychology and decision making in situations involving child sexual abuse

Cátula Pelisoli et al · Universidade de São Francisco, Programa de Pós-Graduação Stricto Sensu em Psicologia · 2011 · ISSN 1413-8271

Este trabalho apresenta uma revisão teórica sobre a tomada de decisão em situações de alegação de abuso sexual infantil. Profissionais de saúde mental em todo o mundo necessitam tomar decisões acerca da veracida...

LCC TENDOlBzeWNob2xvZ3k~Idioma eng

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Technology‐based and digital interventions for intimate partner violence: A systematic review and meta‐analysis

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Technology‐based and digital interventions for intimate partner violence: A systematic review and meta‐analysis

Chuka Emezue et al · SAGE Publishing · 2022 · ISSN 1891-1803

Abstract Background A growing body of research shows the promise and efficacy of technology‐based or digital interventions in improving the health and well‐being of survivors of intimate partner violence (IPV). In ad...

LCC TENDOlNvY2lhbCBTY2llbmNlcw~~Idioma eng

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Use of Sirolimus and Immunoglobulin Replacement Therapy (IRT) in Patients with Activated Phosphoinositide 3-Kinase Delta Syndrome (APDS): A Systematic Literature Review (SLR)

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Use of Sirolimus and Immunoglobulin Replacement Therapy (IRT) in Patients with Activated Phosphoinositide 3-Kinase Delta Syndrome (APDS): A Systematic Literature Review (SLR)

Nicholas L. Hartog et al · Rockefeller University Press · 2026 · ISSN 3065-8993

IntroductionActivated Phosphoinositide 3-Kinase Delta Syndrome (APDS), a rare inborn error of immunity, is associated with immunodeficiency and immune dysregulation. Clinical management includes symptomatic treatment wit...

LCC LCC:Immunologic diseases. AllergyIdioma eng

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Factors Affecting Dimensional Precision of Consumer 3D Printing

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Factors Affecting Dimensional Precision of Consumer 3D Printing

David D. Hernandez · Embry-Riddle Aeronautical University · 2015 · ISSN 2374-6793

This paper investigates the factors affecting dimensional precision of consumer-grade 3D printing, attempting to isolate and mitigate sources of error. The focus is on creating engineering prototypes of, tooling for, or ...

LCC LCC:Motor vehicles. Aeronautics. AstronauticsIdioma eng

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Application of the first canonical variable in the evaluation of animal production trials Aplicação da primeira variável canônica na avaliação de experimentos de desempenho produtivo com animais

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Edenio Detmann et al · Sociedade Brasileira de Zootecnia · 2005 · ISSN 1516-3598

The objective of this work was to evaluate the inter treatment discrimination according to feed conversion efficiency in several animal performance experiments. The variables investigated were: feed conversion ratio (FCR...

LCC LCC:Animal cultureIdioma eng

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Leveraging artificial intelligence to improve data configuration & accuracy in modern flight management systems

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Leveraging artificial intelligence to improve data configuration & accuracy in modern flight management systems

Sreeram Chittayil · Embry-Riddle Aeronautical University · 2024 · ISSN 2374-6793

AI (Artificial intelligence) can automate the process of generating optimized flight routes using real-time data, such as AIRAC (Aeronautical Information Regulation and Control), significantly reducing the time needed fo...

LCC LCC:Motor vehicles. Aeronautics. AstronauticsIdioma eng

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Predictive modeling of punchouts in continuously reinforced concrete pavement: a machine learning approach

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Predictive modeling of punchouts in continuously reinforced concrete pavement: a machine learning approach

Ghazi Al-Khateeb et al · Springer Nature · 2025 · ISSN 2097-0943

Abstract The accurate prediction of the deterioration of Continuously Reinforced Concrete Pavement (CRCP) is essential for the effective management of pavements and the maintenance of infrastructure. In this study, a co...

LCC LCC:Engineering (General). Civil engineering (General); TENDOkluZm9ybWF0aW9uIHRlY2hub2xvZ3k~Idioma eng

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A multi-dimensional transformer encoder framework for modeling fine-grained student programming behavior

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A multi-dimensional transformer encoder framework for modeling fine-grained student programming behavior

Grota Abdelkader et al · Springer · 2026 · ISSN 2948-2992

Abstract Learning to program is not just about writing code. It is a complex process involving trial and error, hesitation, corrections, and sometimes silence. And each student experiences it in their own way. Understand...

LCC LCC:Electronic computers. Computer scienceIdioma eng

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