Buscar recursos académicos

Abstract Background and objectives The under-representation of vulnerable groups in clinical trials, including persons with disabilities, could affect the applicability of trial findings to real-world public health inter...

Abstract Background Alkaline phosphatase (ALP) activity in gingival crevicular fluid (GCF) reflects localized periodontal and alveolar bone remodeling during orthodontic tooth movement. Although ALP changes have been inv...

Abstract Background Previous studies have evaluated traditional Chinese medicine (TCM) clinical randomized controlled trial (RCT) literature broadly, but they have provided limited depth in evaluating the specific aspect...

ABSTRACT Background Regional anesthesia, while offering numerous clinical advantages, can paradoxically heighten intraoperative anxiety and stress due to patients remaining conscious throughout surgical procedures. Objec...

ObjectiveTo evaluate the effects of various transcranial magnetic stimulation (TMS) parameters—including stimulation duration, intensity, pulse number, frequency, and target region—on pain scores in patients with neu...

Background This study aimed to compare the acute and residual physiological responses elicited by three different priming exercise strategies, including high-intensity priming exercise (HIPE), low-intensity priming exerc...

Abstract Background/objectives Cardiovascular diseases (CVDs), particularly myocardial infarction (MI) and heart failure (HF), remain global causes of morbidity and mortality, despite the current treatment options. Stem ...

Abstract Juvenile idiopathic arthritis (JIA) comprises a heterogeneous group of childhood-onset inflammatory arthritides that remain challenging to treat. An expanding range of biologic and targeted synthetic disease-mod...

Abstract Background In the neurorehabilitation framework of treadmill-based robot-assisted gait training (t-RAGT), a threefold relationship among physiotherapist (Pht), patient (Pt), and the selected robotic device shoul...

Abstract BackgroundChronic musculoskeletal pain (CMP) imposes a significant psychological, physical, and emotional burden on millions of adults in the United States. A challenge in treating CMP is its tendenc...

Abstract BackgroundIndividuals with schizophrenia or bipolar disorder face a significantly elevated risk of obesity, primarily due to weight gain associated with psychiatric medications and lifestyle factors....

BackgroundExercises that involve increasing the speed of movements are beneficial for individuals with Parkinson disease (PD) and have the potential to reduce bradykinesia. High-speed bodyweight resistance training is ac...

BackgroundOpioid overdose remains a leading cause of preventable death in the United States. Existing approaches to identify individuals at elevated risk rely on imprecise rule-based criteria that misclassify patients’...

Abstract BackgroundTripterygium glycoside tablets (TGTs), a traditional Chinese medicine–based therapy and a type of conventional synthetic disease-modifying antirheumatic drug (csDMARD), have shown promise...

Objective: To evaluate the efficacy and safety of Ganmai Dazao (GMDZ) decoction alone and in combination with antidepressant medication or psychotherapy for depression. Methods: We searched seven electronic databases fro...

ObjectiveThis review summarizes the current evidence on the impact of isolated antiphospholipid antibody positivity (IAAP) on pregnancy outcomes. It analyzes risk differentials across antibody subtypes, synthesizes the u...

BackgroundStroke remains a leading cause of long-term disability worldwide. Acupuncture has been increasingly integrated into post-stroke rehabilitation programs, yet evidence regarding combined acupuncture protocols rem...

Abstract Background Cold water immersion (CWI) is a common method of post-exercise recovery, but the optimal protocols are not well understood. The lack of exercise-specific guidelines has caused confusion on how CWI sho...

Xiaodong Feng,1 Yuqing Miao,2 Chenhai Zheng,3 Shuai Yuan,3 Jie Qin3 1Department of Hepatobiliary Pancreatic Spleen Thyroid Surgery, General Hospital of Northern Theater Command, Shenyang, 110016, People’s Republic of C...

Drug discovery research faces significant challenges, with around 90 % of candidate drugs failing in clinical trials. Traditional animal models do not always accurately reflect human physiology and pathology, leading to ...

BackgroundResting metabolic rate (RMR) prediction equations used today often rely on the consideration of binary sex. Significant intrasex variability and a lack of data on diverse populations raise concerns about these ...

BackgroundRepetitive peripheral magnetic stimulation (rPMS), a representative non-invasive neuromodulation technique, is widely utilized for the recovery of motor dysfunction following stroke. Although its clinical effic...

Introduction:Orthopedic and musculoskeletal pain is a leading cause of disability worldwide, and many patients continue to experience suboptimal relief despite advances in pharmacological and physical therapies. Magnetic...

Background: Lateral elbow tendinopathy (LET) is a common musculoskeletal disorder caused by overuse, resulting in microtrauma to the extensor tendons. Because of its complex pathophysiology and high recurrence rate, LET ...