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Abstract The dissemination route of brain metastases dictates their spatiotemporal distribution, but whether it alters the ultrastructural state of the blood-tumor barrier remains unresolved. Here, we compared a modified...

ABSTRACT Cancer metastasis is the leading cause of cancer‐related mortality, involving complex interactions between tumor cells and the mechanically heterogeneous tumor microenvironment. The cell nucleus serves as a ce...

In this paper we investigated whether protein kinase C (PKC) b1 and PKCe, members of the classical and novel PKC family respectively, induce phenotypic alterations that could be associated with tumor progression and meta...

Emmanuel Ifeanyi Obeagu1– 3 1Division of Haematology, Department of Biomedical and Laboratory Science, Africa University Mutare, Mutare, Zimbabwe; 2Department of Molecular Medicine and Haematology, School of Pathology,...

Small cell lung cancer (SCLC) remains one of the most aggressive malignancies, characterized by rapid proliferation, early metastatic dissemination, and poor long-term survival despite initial sensitivity to therapy. SCL...

Tumor diseases pose an enormous health threat when they become malignant, as in the process of metastasis. Cancer metastasis has been extensively studied in the past, but attention has been focused primarily on the estab...

Backgrounds Gallbladder cancer is a highly invasive malignant tumor characterized by challenging early diagnosis and poor prognosis. With the widespread adoption of short-video platforms in China, the public increasingly...

Materias / palabras clave: cancer metastasis, metastatic progression, cancer cell migration and invasion, tumor dissemination, translational cancer research; Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogen...