RUNX2 overexpression generates endocrine resistance in human luminal breast cancer xenografts
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CONICET Digital
T47D and IBH6 cells that overexpress RUNX2 show high levels of FGFR2 and FGF2, supporting the hypothesis that FGF2 increases RUNX2 and, in turn, RUNX2 increases FGF2, maintaining a positive loop. However, in these models...
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Open Access