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Materias / palabras clave: Enfermedades del hígado; Diagnóstico médico; Hepatitis; Hepatitis, Viral; Chronic Disease; Alpha fetoproteins; Enfermedades del higado; Diagnostico medico

Gene therapy holds a great potential for treating a variety of human disorders by introducing foreign therapeutic genetic material into target cells using gene carriers (vectors). Most particularly, viral vectors show a ...

Abstract Background Viral infections of tomato plants present a significant threat to tomato production and yield. Mixed viral infections are common in field-grown tomatoes and are known to exacerbate disease symptoms; h...

Abstract Objective The coronavirus disease 2019 (COVID-19) is a pandemic viral disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The impact of the disease among the obstetric population r...

OBJECTIVE: In our study, we aimed to evaluate the history and awareness of hepatitis in HD patients with viral hepatitis who were followed up at our center and in different provinces. MATERIAL and METHODS: A total of ...

ABSTRACT Background and Aims The world has been devastated by the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) from 2019 to 2023 which necessitated stratifying patients into mild, m...

Glycyrrhizin preparations (GLPS), derived from Glycyrrhiza uralensis (licorice), are widely used hepatoprotective agents in clinical practice. Their primary active components, 18α- and 18β-glycyrrhetinic acid (GA), are...

Vaccination is widely used to control foot-and-mouth disease (FMD), necessitating robust approaches for evaluating vaccine potency to ensure a consistent supply of effective and safe vaccines. Traditional (in vivo) poten...

Abstract Tumors and cancer cell lines exhibit varying levels of activation in interferon (IFN) pathways and expression of IFN-stimulated genes (ISGs). This heterogeneity correlates with differential susceptibility to onc...

Abstract Background Limited evidence exists on the prescription patterns of combination antiretroviral therapy (cART) and their effectiveness in achieving HIV-1 viral suppression. This study evaluated pre-conflict prescr...

Disease Diagnosis in crops is a very expensive and lengthy process, as it often involves the need for few experts to make observations, leading to delayed diagnosis, viral spread of diseases, and thus, massive economic l...

The type of mesengial proliferative glomerulonephritis having IgM deposition in DIF examination is called IgM nephropathy. A case performed renal biopsy due to urine findings and diagnosed as IgM nephropathy is presented...

Human herpes infections are a major cause of morbidity worldwide. Herpes Simplex Virus (HSV) and Varicella Zoster Virus (VZV) are frequent causes of ocular pathology. Ocular herpes is a recurrent disease, and its compl...

Herpangina is a self-limiting disease caused by coxsackievirus. The manifestation consists of acute febrile with small ulcerative or vesicular lesions on the tonsillar, soft palate, uvula and buccal mucosa. The disease m...

Abstract Background Cytomegalovirus (CMV) is a ubiquitous herpesvirus with nearly universal seroprevalence in sub-Saharan Africa. In people living with HIV, CMV contributes to immune activation, systemic inflammation, an...

Abstract Background Dolutegravir (DTG) is endorsed as a preferred option for both first- and second-line antiretroviral therapy (ART); however, comprehensive high-quality evidence regarding its virological effectiveness ...

Materias / palabras clave: fusion protein; immune modulation; spike; vaccine; viral entry and infection; viral evasion

Abstract Potato crops in Bangladesh are significantly threatened by viral diseases, underscoring the need for comprehensive virome profiling to inform sustainable management strategies. In this study, we employed high-th...

Abstract Introduction Enterovirus A71 (EV71)–associated encephalitis lacks targeted neuroprotective therapy. Experimental data implicate endoplasmic reticulum (ER) stress and ferroptosis in neuronal injury. We tested w...

Background and AimMost infections are innocuous in most individuals, and most infectious diseases are confined to specific organs. Inborn errors of tissue-intrinsic, non-leukocytic immunity underlie some organ-specific i...

Abstract Background Quarantine and isolation (Q&I) are interrelated but not mutually exclusive public health practices for disease control, which may face public resistance in the context of health emergencies due to ass...

Hepatitis C virus (HCV) infection in patients with chronic kidney disease (CKD) is a major cause of morbidity and mortality. HCV infection is associated with some glomerular disease. It also has a high incidence in patie...

Despite the rapid creation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) vaccines, the precise correlates of immunity against severe Coronavirus Disease 2019 (COVID-19) are still unknown. Neutralizing a...

Despite widespread rollout of dolutegravir-based (DTG) antiretroviral therapy (ART) in East Africa, viral non-suppression, advanced HIV disease (AHD), and multimorbidity persist, reflecting gaps in service response rathe...