Effect of isolated flavonoids from teucrium polium in some of the biochemical variables of healthy and diabetes rats' blood serum

ABSTRACT<br /> This study included preparing aflvonoids extract from teucrium polium plant in which isolating and identifying these compounds by thin layer chromatography (TLC) had been done. The aim of this study is to find the effect of this extract on serum glucose, total cholesterol, triglyceride (T.G), high density lipo protein-cholestrol (HDL-C), low density lipo protein-cholestrol (LDL-C), very low density lipo protein-cholestrol (VLDL-C), total protein and albumin levels in blood serum of normal and alloxan-induced diabetic-albino male rats. Extract was administrated intraperitioneally. The results indicated that there were significant decrease in glucose, total cholesterol and triglyceride levels in normal and diabetic animals which were treated for one week. The results showed that there were no significant changes in the level of high density lipo- protein in normal and diabetic animals which were treated for one week. On the other hand there were significant decrease in the level of low density lipo- protein and very low density lipo-protein in normal and diabetic animals which were treated for week, the result indicated that there were no significant change in the level of total protein and albumin in all treated animals.