Microneedles drug delivery system: insights on its fabrication techniques and challenges

In recent years, there has been significant interest in an innovative transdermal delivery technology. This technology has the ability to distribute therapeutics and cosmeceuticals for various applications, such as vaccines, drugs, and biomolecules for skin-related issues. The advantages of microneedle patch technology have been thoroughly assessed in recent literature, resulting in a substantial increase in academic publications on the topic. However, like any new technology, the application of microneedle patches has potential limitations. In this review, we will discuss these limitations and emphasize the areas that require improvement. Emphasising these concerns early on should help scientists and technologists to address the matters in a timely fashion and to use their resources wisely.