Tubulointerstitial Nephritis and Uveitis (TINU) Syndrome: A Case Report

Tubulointerstitial nephritis and uveitis syndrome is characterized by a combination of acute tubulointerstitial nephritis and uveitis. This syndrome is an uncommon cause of acute tubulointerstitial nephritis and is an exclusion diagnosis. Most patients with this syndrome are young women and adolescents although it may occur adults and old age. The uveitis can occur concurrently, precede or follow the onset of the tubulointerstitial nephritis. The vast majority of cases present after the onset of renal disease. The underlying mechanisms of the disease are still unknown. Renal disease tends to be self-limited, whereas uveitis tends to recur and relapse. A collaborative approach between nephrologists and ophthalmologists is crucial for the early diagnosis, treatment and management of disease. In this report, we describe a 31-year-old woman with tubulointerstitial nephritis and uveitis syndrome.