ATYPICAL HEMOLYTIC UREMIC SYNDROME: REPORT OF A PEDIATRIC CASE

Atypical hemolytic uremic syndrome (HUS) is a rare disease in childhood. The morbidity and mortality of this disease is found high. In this report, a 13 years old boy who had five times of HUS attacks was presented. The family history revealed that his uncle was on hemodialysis for chronic renal failure. The patient had acute renal failure, hemolytic anemia, thrombocytopenia, and dark urine when he was first hospitalized. HUS was diagnosed based upon his clinical and laboratory findings. During the follow-up, he developed three more attacks when he was five, six, nine and ten years old which all required admission to the hospital. The last attack occurred when he was ten years old and plasmapheresis required for five times. He had a quick response to it. We suggest that plasmapheresis is an effective treatment approach in cases with atypical HUS.