HEMOPERFUSION IN AMANITA PHALLOİDES POISONING: REPORT OF TWO CASES

Amanita phalloides mushrooms are extremely toxic. Alpha-amanitin is an amatoxin known to produce deleterious effects on the liver and the kidneys, when circulating in the blood. Different therapeutic approaches are employed to treat mushrooms intoxication such as hemoperfusion, high doses of penicillin G, oral charcoal, force diuresis and liver transplantation. Two brothers with Amanita phalloides poisoning were admitted with gastrointestinal symptoms beginning ten hours following the ingestion. Neither of patients had hepatomegaly. Liver function tests were foundts be high in both of them. Hemoperfusion and supportive therapy were performed. Liver enzymes returned to the normal level after 20 days. Both children recovered from this fatal condition. The life saving role of early hemoperfusion in amanita phalloides is emphasized.