Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking

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Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking

Thomas Opsommer et al · Elsevier · 2026

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Autore / responsabile

Thomas Opsommer et al

Editore

Elsevier

Anno

2026

ISSN

2405-6316

ISSN

2405-6316

Lingua

Inglés

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Free-breathing spine-based positioning/tracking in lung stereotactic body radiotherapy is required when direct tumor positioning is not possible. Respiratory baseline, motion and target position reproducibility interact and remain uncertainty sources. This results in conflicting margins but also clinical control. The internal target volume geometric reproducibility, spine distance dependency and four-dimensional per-fraction gross tumor volume (GTV) dose was analyzed in 340 fractions. While the target would leave a projected isotropic 5 mm planned target volume in 11% of fractions, ΔD98%(4D-GTV) > 10% occurred in 2.6% of fractions. Risk mitigation is suggested through additional off-line 4DCT, surface guidance, fractionation and increased inferior-superior and posterior-anterior margins.

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APA 7

al, T. O. E. (2026). Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking. https://doi.org/10.1016/j.phro.2026.100944

MLA

al, Thomas Opsommer et. "Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking." 2026. https://doi.org/10.1016/j.phro.2026.100944.

Chicago

al, Thomas Opsommer et. 2026. "Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking.". https://doi.org/10.1016/j.phro.2026.100944.

Harvard

al, T. O. E. 2026, Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking, Elsevier, available at: https://doi.org/10.1016/j.phro.2026.100944 [Accessed 8 Aug. 2026].

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Titolo: Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking

Autore / collaboratori: Thomas Opsommer et al

Editore: Elsevier

Anno di pubblicazione: 2026

ISSN: 2405-6316

ISSN: 2405-6316

Lingua: Inglés

Soggetti

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Internal target volume; Lung tumors; 4D Cone Beam CT; Image-guided Radiotherapy; Stereotactic body radiotherapy