Recent advances in TGF-β signaling: insights into regulation, pathophysiological function, and clinical translation

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Recent advances in TGF-β signaling: insights into regulation, pathophysiological function, and clinical translation

Xiaohua Yan et al · SpringerOpen · 2026

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Autor / responsable

Xiaohua Yan et al

Editorial

SpringerOpen

Año

2026

ISSN

2045-9769

ISSN

2045-9769

Idioma

eng

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Abstract Cytokines from the transforming growth factor-β (TGF-β) superfamily are essential regulators of cell growth, survival, and differentiation, playing a pivotal role in mammalian embryonic development, adult tissue homeostasis, and progression of human diseases. Recently, an international symposium on TGF-β Signaling in Development and Diseases was held in Nanchang, China, from October 21 to 23, 2025. This event showcased the latest advances in TGF-β signaling and its pathophysiological functions. Over ten presentations at the symposium offered new insights on Smad-dependent and non-Smad TGF-β signaling, its spatiotemporal regulation, and multifaceted roles of TGF-β family cytokines in various pathophysiological contexts. The symposium also addressed potential strategies and opportunities for targeting the TGF-β pathway in the treatment of human diseases.

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APA 7

al, X. Y. E. (2026). Recent advances in TGF-β signaling: insights into regulation, pathophysiological function, and clinical translation. https://doi.org/10.1186/s13619-026-00286-w

MLA

al, Xiaohua Yan et. "Recent advances in TGF-β signaling: insights into regulation, pathophysiological function, and clinical translation." 2026. https://doi.org/10.1186/s13619-026-00286-w.

Chicago

al, Xiaohua Yan et. 2026. "Recent advances in TGF-β signaling: insights into regulation, pathophysiological function, and clinical translation.". https://doi.org/10.1186/s13619-026-00286-w.

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al, X. Y. E. 2026, Recent advances in TGF-β signaling: insights into regulation, pathophysiological function, and clinical translation, SpringerOpen, available at: https://doi.org/10.1186/s13619-026-00286-w [Accessed 29 Jun. 2026].

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Título: Recent advances in TGF-β signaling: insights into regulation, pathophysiological function, and clinical translation

Autor / colaboradores: Xiaohua Yan et al

Editorial: SpringerOpen

Año de publicación: 2026

ISSN: 2045-9769

ISSN: 2045-9769

Idioma: eng

Materias

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TGF-β superfamily; Signaling regulation; Stem cells; Embryonic development; Cancer; Clinical translation