Novedades Ayuda Acceso institucional
← Volver a resultados
Ficha bibliográfica · Consulta y acceso
Artículo

Gastro-resistant pellets of didanosine obtained by extrusion and spheronization: assessing the production process

Andréo Filho, Newton et al · SEDICI UNLP · 2009

Material complementario disponible
Lectura rápida. Revisá los datos básicos del recurso y luego accedé al contenido desde el botón principal. En esta ficha solo se muestra la información necesaria para identificar la obra, citarla y abrirla.
Autor / responsable
Andréo Filho, Newton et al
Editorial
SEDICI UNLP
Año
2009
Idioma
en

Acceso al recurso

Entrá al contenido desde la opción principal o elegí otra fuente disponible.

Acceso principal

Material complementario disponible

El enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.
Abrir material

Resumen

Descripción general del contenido del recurso.

The aim this work was develop gastro-resistant pellets of didanosine as well as study the impact on the pellets properties, regarding the way as the binder was added and drying process used. The pellets formation was accompanied by analysis of morphological parameters and didanosine dissolution. In the most cases, pellets showed diameter around 1.0 mm and shape parameters acceptable. The variations of the process did not interfere significantly in pellets size. In turn, drying in fluid bed favored the dissolution of didanosine, in contrast to binder addition on powder form that impaired. In another hand, this last resulted in the best aspect factor (about 1.1). Gastro-resistant pellets showed adequate dissolution, compatible with this type of dosage form. The variables of process studied enabled obtain pellets with
characteristics of shape and dissolution just slightly different, indicating flexibility of the formulation for production of gastro-resistant pellets of didanosine.
Colegio de Farmacéuticos de la Provincia de Buenos Aires

Cómo citar

Elegí el formato que necesitás y copiá la referencia al portapapeles.

APA 7

Andréo Filho, N. E. A. (2009). Gastro-resistant pellets of didanosine obtained by extrusion and spheronization: assessing the production process. http://sedici.unlp.edu.ar/handle/10915/7722

MLA

Andréo Filho, Newton et al. "Gastro-resistant pellets of didanosine obtained by extrusion and spheronization: assessing the production process." 2009. http://sedici.unlp.edu.ar/handle/10915/7722.

Chicago

Andréo Filho, Newton et al. 2009. "Gastro-resistant pellets of didanosine obtained by extrusion and spheronization: assessing the production process.". http://sedici.unlp.edu.ar/handle/10915/7722.

Harvard

Andréo Filho, N. E. A. 2009, Gastro-resistant pellets of didanosine obtained by extrusion and spheronization: assessing the production process, SEDICI UNLP, available at: http://sedici.unlp.edu.ar/handle/10915/7722 [Accessed 23 Jun. 2026].

Compartir e imprimir

Guardá la ficha, copiá su enlace permanente o imprimila como PDF.

Exportar referencia

Si usás un gestor bibliográfico, podés exportar el registro en los formatos más comunes.

RIS BibTeX

Detalles del recurso

Información bibliográfica útil para confirmar que se trata del material correcto.

Título
Gastro-resistant pellets of didanosine obtained by extrusion and spheronization: assessing the production process
Autor / colaboradores
Andréo Filho, Newton et al
Editorial
SEDICI UNLP
Año de publicación
2009
Idioma
en

Materias

Explorá otros recursos relacionados a partir de estas materias.

Farmacia; Medicamento; didanosine; extrusion; gastro-resistant dosage form; pellets; spheronization; Formas de Dosificación; Inosina
Copiado