Additional evidence for the anti-inflammatory properties of the essential oil of Protium heptaphyllum resin in mice and rats

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Additional evidence for the anti-inflammatory properties of the essential oil of Protium heptaphyllum resin in mice and rats

Amaral, Maurício P.M. et al · SEDICI UNLP · 2009

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Autor / responsable

Amaral, Maurício P.M. et al

Editorial

SEDICI UNLP

Año

2009

Idioma

en

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The objective of this study was to analyze the chemical composition and evaluates further the anti-inflammatory properties of essential oil of Protium heptaphyllum resin (EOP). The essential oil was analyzed by GC/MS. Fourteen constituents, accounting for 100% of the total oil, were identified. The main constituents of essential oil were limonene (49.96%), trans-β-ocimene (11.81%), eucalyptol (10.92%) and p-cymene (10.78%). EOP administered orally (100 and 200 mg/kg b.w.) significantly suppressed the development of carrageenan and egg albumin-paw edema and produced a significant inhibition of peritoneal vascular permeability induced by acetic acid. OEP also reduced peritoneal leukocytes migration, granuloma tissue formation and mast cell degranulation induced by compound 48/80 (ex-vivo). These results appear to support the potential medicine use of EOP against inflammatory conditions. Colegio de Farmacéuticos de la Provincia de Buenos Aires

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APA 7

Amaral, M. P. E. A. (2009). Additional evidence for the anti-inflammatory properties of the essential oil of Protium heptaphyllum resin in mice and rats. http://sedici.unlp.edu.ar/handle/10915/7835

MLA

Amaral, Maurício P.M. et al. "Additional evidence for the anti-inflammatory properties of the essential oil of Protium heptaphyllum resin in mice and rats." 2009. http://sedici.unlp.edu.ar/handle/10915/7835.

Chicago

Amaral, Maurício P.M. et al. 2009. "Additional evidence for the anti-inflammatory properties of the essential oil of Protium heptaphyllum resin in mice and rats.". http://sedici.unlp.edu.ar/handle/10915/7835.

Harvard

Amaral, M. P. E. A. 2009, Additional evidence for the anti-inflammatory properties of the essential oil of Protium heptaphyllum resin in mice and rats, SEDICI UNLP, available at: http://sedici.unlp.edu.ar/handle/10915/7835 [Accessed 29 Jun. 2026].

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Título: Additional evidence for the anti-inflammatory properties of the essential oil of Protium heptaphyllum resin in mice and rats

Autor / colaboradores: Amaral, Maurício P.M. et al

Editorial: SEDICI UNLP

Año de publicación: 2009

Idioma: en

Materias

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Farmacia; Farmacología; actividad anti-inflamatoria; aceite esencial; limoneno; Protium heptaphyllum; Plantas medicinales; anti-inflammatory activity; essential oil; limonene; mast cells; Protium heptaphyllum