Influence of the addition of alpha or gamma-cyclodextrin on the formation of free films in the polymethacrylates eudragit® FS30D

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Influence of the addition of alpha or gamma-cyclodextrin on the formation of free films in the polymethacrylates eudragit® FS30D

Melo, Emerson J. et al · SEDICI UNLP · 2010

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Autor / responsable

Melo, Emerson J. et al

Editorial

SEDICI UNLP

Año

2010

Idioma

en

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Free films were obtained by the combination of a polymer EudragitTM FS30D and oligosaccharides (alpha or gamma-CDs), by a casting process. The films were characterized by DSC, TGA, FTIR and SEM. The influence of composition was available by WVT and swelling measurements experiments. The DSC, TGA and FTIR characterized the films as immiscible in all composition studied. The results have shown that the addition of oligosaccharide to EudragitTM FS30D promoted changes to both the water vapour permeability and hydration properties of the films. The changes were shown to be dependent on the increase in the concentration oligosaccharides added to the free film. The films EudragitTM FS30D and oligosaccharides alpha or gamma-CDs obtained are regarded as being suitable for preventing the premature release of drugs in the upper part of the gastrointestinal tracts and present great interest in the application as biodegradable carriers for modified oral drug delivery systems. Colegio de Farmacéuticos de la Provincia de Buenos Aires

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APA 7

Melo, E. J. E. A. (2010). Influence of the addition of alpha or gamma-cyclodextrin on the formation of free films in the polymethacrylates eudragit® FS30D. http://sedici.unlp.edu.ar/handle/10915/8005

MLA

Melo, Emerson J. et al. "Influence of the addition of alpha or gamma-cyclodextrin on the formation of free films in the polymethacrylates eudragit® FS30D." 2010. http://sedici.unlp.edu.ar/handle/10915/8005.

Chicago

Melo, Emerson J. et al. 2010. "Influence of the addition of alpha or gamma-cyclodextrin on the formation of free films in the polymethacrylates eudragit® FS30D.". http://sedici.unlp.edu.ar/handle/10915/8005.

Harvard

Melo, E. J. E. A. 2010, Influence of the addition of alpha or gamma-cyclodextrin on the formation of free films in the polymethacrylates eudragit® FS30D, SEDICI UNLP, available at: http://sedici.unlp.edu.ar/handle/10915/8005 [Accessed 29 Jun. 2026].

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Título: Influence of the addition of alpha or gamma-cyclodextrin on the formation of free films in the polymethacrylates eudragit® FS30D

Autor / colaboradores: Melo, Emerson J. et al

Editorial: SEDICI UNLP

Año de publicación: 2010

Idioma: en

Materias

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Farmacia; acrilic polymer; alpha-cyclodextrin; biodegradable carriers; gamma-CDs cyclodextrin; free film; Farmacología; Polímeros; Evaluación de drogas