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Molecular detection and phylogenetic relationship of wild-type strains of canine distemper virus in symptomatic dogs from Uberlândia, Minas Gerais

S.A. Headley et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2015

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This study investigated the occurrence of canine distemper virus (CDV) by evaluating the presence of viral RNA within urine samples of dogs from Uberlândia, MG, with clinical manifestations suggestive of infection by CDV by targeting the CDV N gene. Of the clinical samples collected ( n =33), CDV viruria was detected in 45.5%. Five dogs died spontaneously; all had characteristic CDV-associated histopathological alterations and demonstrated CDV viruria. Statistical analyses revealed that the age, gender, breed, or the organ system of the dog affected had no influence on the occurrence of canine distemper. Myoclonus and motor incoordination were the most significant neurological manifestations observed. A direct association was observed between keratoconjunctivitis and dogs with CDV viruria. These findings suggest that CDV viruria in symptomatic dogs might not be age related, and that symptomatic dogs can demonstrate clinical manifestations attributed to CDV without viruria identified by RT-PCR. Additionally, the results of the sequence identities analysed have suggested that all Brazilian wild-type strains of CDV currently identified are closely related and probably originated from the same lineage of CDV. Nevertheless, phylogenetic analyses suggest that there are different clusters of wild-type strains of CDV circulating within urban canine populations in Brazil.

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APA 7

al, S. H. E. (2015). Molecular detection and phylogenetic relationship of wild-type strains of canine distemper virus in symptomatic dogs from Uberlândia, Minas Gerais. https://doi.org/10.1590/1678-4162-7052

MLA

al, S.A. Headley et. "Molecular detection and phylogenetic relationship of wild-type strains of canine distemper virus in symptomatic dogs from Uberlândia, Minas Gerais." 2015. https://doi.org/10.1590/1678-4162-7052.

Chicago

al, S.A. Headley et. 2015. "Molecular detection and phylogenetic relationship of wild-type strains of canine distemper virus in symptomatic dogs from Uberlândia, Minas Gerais.". https://doi.org/10.1590/1678-4162-7052.

Harvard

al, S. H. E. 2015, Molecular detection and phylogenetic relationship of wild-type strains of canine distemper virus in symptomatic dogs from Uberlândia, Minas Gerais, Universidade Federal de Minas Gerais, Escola de Veterinária, available at: https://doi.org/10.1590/1678-4162-7052 [Accessed 29 Jun. 2026].

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Título
Molecular detection and phylogenetic relationship of wild-type strains of canine distemper virus in symptomatic dogs from Uberlândia, Minas Gerais
Autor / colaboradores
S.A. Headley et al
Editorial
Universidade Federal de Minas Gerais, Escola de Veterinária
Año de publicación
2015
ISSN
1678-4162
ISSN
1678-4162
Idioma
eng

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