Production of antibiotic of Microlides group from a local isolate of the bacterium Streptomyces rimosus

<span>Three local isolates of the genus </span><span>Streptomyces</span><span> were obtained from ten soil samples collected from different places of Niniva governorate. The isolates showed bioactivity against test Gram positive and negative bacteria and two Genera of fungi. </span><span>Streptomyces</span><span> isolates were identified according to microscopic and morphological tests. The </span><span>Streptomyces</span><span> isolates were subjected to ultra violet ray for different time periods. The treated isolates showed little increase in inhibition zone and treated period of (5) minutes showed the best inhibition of the test bacteria. The</span><span> Streptomyces</span><span> isolates treated with N – methyl – N – nitro – N – nitroso guaniction at the concentration of (50) </span><span> showed clear increase of antibiotic production. The isolate </span><span>Streptomyces</span><span> III showed clear inhibition against </span><span>Escherichia coli</span><span>, </span><span>Pseudomonas aeruginosa</span><span> and </span><span>Bacillus subtilis </span><span>and the diameter inhibition zone was (20,29,20)mm respectively.</span>